Emerging Phenomenological and Biological Principles of Consciousness: Top Insights of Prevailing Models, Concepts, and Observations

We are all aware that our experience is structured into left and right, up and down, and we can understand from our own experience that consciousness is unified into a singular whole. Although we can understand such basic phenomenological axioms of experience, there are many more principles that we cannot elucidate from our natural perspective alone. In this article, we review potential principles of consciousness revealed by prominent consciousness models, theories, and experimental observations such as the Default Space Theory, Operational Architectonics Theory, and Integrated Information Theory, which reveal biological and phenomenological foundations upon which consciousness is formed and maintained. The fundamental concepts we explore and consider worthy have largely emerged from commonalties shared by the various models which have gained attention. The concepts we review include the unity of consciousness, bioelectric operations as the substrate of consciousness, the emergence of a virtual 3D matrix, and the top-down dominance of perception.

• Default Space
• Consciousness
• Thalamus
• Perception
• Operational Architectonics
• Integrated Information Theory
• Neural Synchrony
• World Simulation

1. Introduction

(Phenomenal) Consciousness as we address it is a subjective, personal experience; a type of phenomenon that seems non-physical [1] , but is tightly anchored to physical-biological reality [2] . The best way to describe it for our purposes and in general is that of “pure experience” [3] [4] [5] . It may appear to many neuroscientists, physicists, and other thinkers that the only bigger mystery than the nature of phenomenal consciousness that exists in modern science is perhaps the origin and ultimate physical nature of the universe. The harder to solve aspect of the mystery of consciousness can be divided into two main sub-problems; what are the conditions that determine if a system is conscious, and what are the conditions that result in the many differentiated states of consciousness [6] ? By determining certain axioms about phenomenal consciousness that we can be certain of from our own experience of being a conscious person, we can gain insight into and even derive further biological mechanisms that may solve easier problems of consciousness [7] .

Science cannot completely penetrate many technicalities when studying consciousness due to its subjective quality, very different than the physical and mathematical realms in which it normally operates. However, when we study consciousness through the lens of our own experience in combination with scientific research, then we can truly advance towards demystifying it. In this article, we review concepts we consider principles of consciousness that have been established by various distinguished models and research. We review these concepts through the lens of the Default Space Theory which was developed in part via prolonged phenomenological observation of the structure of subjective experience [8] . It could be argued that the nature of consciousness is too complex and elusive for the current scientific community to establish any certainties about it. We suggest however that some aspects about its phenomenology are undeniable (such as that is exists [9] ), and some biological explanations for its emergence are highly persuasive. We may be a great distance away from understanding how certain physical systems can give rise to consciousness; however, we can still open this frontier for exploration by understanding its basic phenomenological and biological aspects [1] .

2. The Default Space Theory

The principles of consciousness we suggest in this article are largely components of the Default Space Theory (DST) that are shared with other prominent models. The DST is different from other popular metastable models of consciousness in that it is not brain-centric, but an embodied model that propounds consciousness emerges from the body as well as the brain [8] . The DST explains how sensory information originating from external stimuli, internal visceral stimuli, and mental generation is processed, integrated, and filled into a spatial, three dimensional, internal virtual simulation of the external world [8] . Consciousness is in a way identical to this space termed the default space, and it can be thought of as the architectural structure of consciousness. The thalamus is the center of this global bioelectric space, orchestrating the emergence of the space as an informational hub [8] . The default space provides the medium for replication of the external environment in order to provide optimal interaction within the natural physical and ecological environment [10] . In suggesting potential fundamental principles of consciousness, this article while will have a bias towards this theory’s perspectives.

The DST is also unique in its description of the architecture of the bioelectric framework isomorphic to phenomenal mind. The stress put on the thalamus as a key component of a holistic bioelectric system helps explain some of the top mysteries of mind [11] . The DST describes this bioelectric system as a frequency-based hierarchy which includes bodily rhythms at the foundation [12] . The DST helps answer the binding problem by describing how the thalamus uses reentrancy or looping activity to coordinate and unify widespread cortical activity into a macroscopic bioelectric structure [8] . In addition, by describing the physiological nature of the 3D virtual matrix of consciousness, it provides a means to further explain how diverse multimodal cortical modules are unified and what biological function consciousness really emerges from (creation of an internal simulation of the world) [13] . By describing biological processes in relation to a default virtual construct, it describes how we may have a seamless experience as the current simulation of the world also provides top-down context allowing for quick integration of new information.

3. Consciousness as a Unified Virtual Construct

Although some early thinkers such as Jung criticized the idea [14] , a common assumption in many consciousness conceptualizations is the unified and singular nature of consciousness. Although it is interesting to ponder whether multiple, separate, and phenomenologically distinct consciousnesses exist within one human being, which may be the case in split-brain syndrome [15] [16] , it is commonly believed that a singular consciousness experience is attributed to any healthy person. Some neuroscientists believe that the hundreds or thousands of mesoscopic processing modules in each brain may possess its own consciousness [17] . Modern models emphasize that while although there may be multiple consciousnesses in one brain (on different levels assuming consciousness can be quantified), each phenomenal consciousness is independent and itself a unified virtual construct [7] [15] . The term virtual is used to describe a phenomenal experience for the same reason a computer-generated reality is. The nonmaterial virtual reality of a computer does not exist physically in the computer, and the same can be said of phenomenological reality not existing physically in the brain [2] .

The Integrated Information Theory ( IIT ) proposed by Tononi posits such a unified nature of experience as self-evident, and it is one of its axioms of consciousness along with its spatial structure and irreducibility [7] . IIT is unique as it describes the substrate of phenomenological experience not only biologically, but physically, tying consciousness to any unified physical system that processes information in a certain way while also being irreducible in its repertoire of potential cause and effect relationships [7] [15] . The DST shares this common perspective of prevailing models on the biological explanation of such phenomenal unity. That being consciousness is not the product of specific neural sites in the brain, but is the result of a prodigious (neuro) biological system that the DST asserts extends to the body [18] [19] . In addition to the unification of cognitive acts across diverse areas of the brain [20] , if the qualia of experience are unified, there must a mechanism to unify all of the neural information isomorphic to the qualia contained in that experience [21] . The dynamic variations, synchronies, and signals of bioelectric neural oscillations may provide the medium for such phenomenal unity [1] [11] [19] . The unified and integrated phenomenal experience is thus suggested to be isomorphic to a bioelectric, unified metastable continuum (UMS) across the brain [1] [22] , and potentially the body [8] . The UMS is a dynamic, hierarchical, bioelectric architecture of macroscopic level [22] . Via similar correlates, some have even suggested consciousness extends to the environment [19] .

4. Consciousness as a Simulation of the External World

Optical illusions provide a first-person account of the true nature of consciousness, that we do not directly perceive actual reality, however, we perceive a subjective version of it. According to several models and researchers, the phenomenal reality we experience is a virtual one and may be functionally understood to emerge from or be identical to a simulation or model of the external, objective reality [2] [11] [23] [24] . This includes modeling of the self [25] [26] . The notion that a main function of the brain is to internally model the external environment and internal processes originated in the earliest days of cognitive science [27] , and the founding principles of simulation theory go back to the 18^th century [28] .

Modeling the external world is a crucial animalian survival mechanism [29] . As an interesting active sensing example, bat brains create three-dimensional (3D) spatial models of their environment using their own reflected sound waves [30] . Even modern robotics methods interact and understand the world by simulating the robot’s environment and its relationship to it [31] . We assert that considering the contents consciousness as a recreation and not a direct perception is an undeniable reality supported by basic logic and research. Thus, the contents of consciousness can be considered a simulation.

Several of these simulation models suggest the phenomenal foundation of this simulation is a (un/sub) conscious, 3D coordinate matrix, or virtual space, in which all qualia are embedded [8] [26] [32] . This virtual space explains how the contents of consciousness are unified and integrated into one experience [2] [13] and may bridge the gap between biological systems and phenomenal consciousness [32] . It is suggested to be functionally isomorphic to certain lower-complexity (un/subconscious), electrophysiological components of a UMS [1] [32] . The DST has propounded that the ultraslow (<0.1 hz) oscillations, which act over much larger distances [33] and neuronal groups compared to higher frequencies [34] , are the component which creates the framework isomorphic to this virtual 3D matrix [13] . It has termed this virtual space the default space as the external world is defaulted within it [8] .

The Fingelkurts describe such level of brain activity isomorphic to the phenomenal structure of mind as the operational architectonics level [32] . They point to a variety of research [35] [36] [37] to suggest phenomenal consciousness arises when a certain bioelectric architecture dominated by alpha and beta oscillations is maintained [38] . They suggest however that the subconscious 3D matrix is constituted not only of networks of oscillations, but also the material networks of neuronal assemblies [32] . Although this virtual matrix is un/subconscious, via meditative practices, one may become more aware of its underlying presence [39] . The functional necessity of such a 3D matrix underlying human, if not all animalian, experience is demonstrated in contralateral neglect syndrome [32] [40] (Figure 1).

We may feel that our awareness is a firsthand experience of reality, however, it is heavily influenced by our expectations, past experiences, and biases instead of a direct experience of external stimuli [2] [24] [41] [42] [43] In this way, we experience an “informed hallucination”, or best guess of the world [43] . The nature of this hallucination is revealed in first-person observations. For instance, the “blind spot”, which is the area of the retina lacking photoreceptor cells where the optic nerve passes through the optic disc, reveals how capable the mind is of creating realistic perceptions [44] . When one eye is closed, the brain fills in the blind spot with surrounding visual patterns, giving the illusion of a seamless, external, and unaltered visual experience [45] .

Several modern models identify consciousness with a simulation of reality, the self, and organisms-environment interaction. Revonsuo may have been the first to use a metaphor of virtual reality to describe such an internal simulation [2] . Many of the world-simulation models point to dreaming as strong evidence of the brain’s ability produce its own subjective experiential reality [2] [8] [32] [46] , with 90% of dreams being experienced as real within a spatially extended virtual reality [47] [48] . Nightmares likely serve as a defense mechanism to simulate dangerous situations in order to practice escaping from these situations such as running from a bear [49] . The threat-simulation theory proposed by Revonsuo formally describes such a simulation defense mechanism that leads to more efficient threat perception and avoidance [50] . Dreams thus show the functional value of simulation.

Trehub’s Retinoid model attempts to describe how the brain produces such an internal model of its intimate world via a minimal neural system that combines disparate sensory stimuli into a unified representation [26] . Metzinger’s Self-Model theory of Subjectivity explores how the “self” does not truly exist; however, we simulate a model of a self. Although there is a phenomenal distinction between this simulation of self and the simulation of the external world, the self is still an internal, virtual representation of our mental and physical being [25] . Philosopher and cognitive scientist Rick Grush has proposed an information-processing strategy termed the emulation theory of representation which explains how the

brain produces neural circuits that model the body environment [24] . He describes mathematically how these models run in parallel with the body and environment in order to provide top-down expectations which enhance and process sensory information. This top-down nature of perception is another principle which we explore later in this article.

Robert Gordon has applied such a simulation theory to the “theory of mind”, in which we can understand other’s actions and perceptions through simulating them [51] . Hesslow describes how thinking and the inner world of consciousness consist of simulated interaction with the environment [23] . He identifies the simulated inner world as an evolutionary fundamental function of the brain and uses the simulation hypothesis to tie together actions, perceptions, and cognitive functions, explaining why imagining activities such as playing tennis leads to the occurrence of activity in perceptual and motor neural structures that would be present [52] if one was actually playing tennis [23] . We suggest this active, internal 3D simulation is the central cognitive, perceptual, and behavioral framework of mind in potentially all animals. The default mode network ( DMN ) may play a direct role in the maintenance such a simulation [39] [53] . The high levels of energy that would be required to continually maintain such a simulation may provide an explanation for why DMN and other intrinsic brain activities utilize ~90% of the brain’s energy [54] [55] .

5. The Thalamus as a Central Hub

Based on significant research [56] [57] [58] , the thalamus, via its hub role in the thalamocortical system, has been described by prevailing theories of consciousness as essential to consciousness [8] [59] . IIT, which proposes that consciousness arises from irreducible physical systems which integrate information in a certain manner, has described the distributed thalamocortical network as the neural substrate of consciousness [6] due to its specialization (rapid and effective interactions) in integrating information from within and among distributed cortical areas [60] [61] . This network is organized for a metastable activity, promoting both specialization of cortical sites and their integration into a greater, more abstract network [6] [62] . A theory also developed in part by Tononi, the Dynamic Core Hypothesis (DCH), describes a unified, dynamic, widespread, information integrating system or “core” as the correlate of consciousness composed of synchronous, reentrant activity among interconnected corticortical and corticothalamic networks [63] [64] . The GWT also identifies the corticothalamic system as the candidate for a substrate of unified consciousness or “workspace” which allows for a globally functional system of bidirectional signaling, binding information from independent, unconscious modules [65] .

The thalamic hub includes about fifty nuclei that connect the sensory organs with respective cortical projections [66] . The thalamus is also suggested as a hub of consciousness due to its coordination and rich reentrant connectivity throughout the cortex [8] [59] which may allow for large-scale oscillatory harmony necessary for an integrated experience [32] . It is like the conductor of a vast bioelectric orchestra of mind. According to the DST and other metastable models just mentioned, the thalamus is the main integrator of global information, coordinating a global oscillatory framework largely through corticothalamic feedback loops [8] . The thalamus is the medium through which the cortex “talks to itself” [67] , allowing any cortical array to signal any other [68] . In this way, the thalamus is the central server in a “World-Wide-Web” of the cortex in which any cortical site can contact any other [65] [69] .

Baars ties this “any-to-any” broadcasting to the binding of sensory perceptions into a unified whole, and identifies activity which broadcasts globally as the activity rising to consciousness; therefore, no single corticothalamic location is privileged to consciousness [65] . Clearly, however, the thalamus is privileged to consciousness as it is required for the essential thalamocortical-corticothalamic network to exist. Dehaene and Changeux have extended Baars global workspace theory into a more neural implementation termed the global neuronal workspace [70] . They describe how the thalamus allows for global activity patterns among multiple brain systems that create a meta neural network leading to consciousness [71] .

In similarity to the DST, Ward discusses in his thalamic dynamic core theory that although the cortex computes the contents of perception, the thalamus is responsible for “displaying” those contents and thus creating the perceptual experience [72] . In his view we support, experience occurs when the cortex “informs” or synchronizes with the respective thalamic nuclei its activity which is integrated into the thalamic dynamic core or unified metastable continuum and thus its isomorphic, phenomenal counterpart, the default space of the DST [8] . The thalamic dynamic system described by Ward and by the DST consist of bioelectric neural (and non-neural according to the DST) synchrony, and thus such synchrony is proposed as the ultimate neural correlate of consciousness [72] .

The DST asserts a much stronger role of the thalamus compared to other metastable models, with some metastable models asserting that consciousness can occur anywhere throughout the cortex with disregard to the thalamus [1] [32] . As discussed previously, the DST asserts that the unified bioelectric architecture which is the foundation of consciousness is organized, synchronized, and harmonized by the thalamus, [11] , and that it “fills” in perceptual qualia generated across specialized cortical sites into the 3D virtual matrix [8] whose isomorphic counterpart is found across the brain and possibly body [13] . The DST explains how the thalamus, in a sense, “views” the entire bioelectric structure surrounding it which is supported by that fact that it represents a core, convergent, miniaturized map of the cortex and sensory organs [72] .

The thalamic intralaminar nuclei project reentrant connections widely to all cortical areas, and their destruction can result in a permanent loss of consciousness [73] . Removal of other large portions of the cortex and brain however often do not significantly diminish consciousness, demonstrated by its persistence after the removal of the frontal cortex [74] , hippocampus [75] , cerebellum [76] , and even an entire cerebral hemisphere [77] . Even removal of small portions of the thalamus can lead to significant cognitive problems [78] , and thalamic deep brain simulation may restore consciousness to patients in coma and vegetative states [79] . The thalamus relays all sensory information to the cortex and contrary to prevailing views also relays olfaction [80] . In addition, it also is involved in sensory processing [81] and multi-sensory integration [82] . Most anesthetics seem to temporarily terminate consciousness via a “hyperpolarization blocking” of relay nuclei of the thalamus [83] , and a similar mechanism is observed in deep sleep [84] .

The internal template of the world in which consciousness “inhabits” parallels the physical qualities of the external world. We have proposed how spatial planes of experience such as horizontal, vertical, radial, anterior, and posterior exist respective of one’s thalamus [8] . Phenomenal experience consists of a direct presence at the center of an externalized, spatially based (virtual) reality [2] [26] . We speculate this sense of the self-center exists in respect to this physical location of the thalamus because of its significance as the “center of mass” of the bioelectric architecture of the mind. Although cortical areas likely generate this sense of self and its localization [85] [86] , it may virtually map this phenomenal sense of self-center to the thalamus. If one closes their eyes and tries to pinpoint the exact location of their perspective, they will find it exists slightly above and behind the eyes, which is the anatomical location of the thalamus.

The significance of a “topographic map of the self” in which the self is centered at the most relevant anatomical location may be similar to benefits produced by other topographic maps which include metabolic benefits [87] , improved connectivity, reductions in neural volume [88] , and possibly operational improvements or requirements to the functional bioelectric architecture producing consciousness. The placement of self-center in the head is by no means a functional or anatomical requirement. This is demonstrated by out-of-body experiences [89] . The plasticity of self-perception allows for people to adopt and control new bodies as their own through modern virtual reality technology [90] . The virtual body can be attributed by the participant as their own physical self, providing perceived agency over this virtual body as the participant further attributes its actions as their own [91] . Thus, if self-center is truly localized at the thalamus, this may suggest its anatomical and/or functional importance.

6. An Isomorphic, Bioelectric, Metastable Architecture of Consciousness

The DST [11] [13] , Operational Architectonics Theory (OAT) [32] , and others [2] [19] [59] discuss in varying perspectives an isomorphism between the unified nature of human experience and a unified, metastable, bioelectric construct consisting of functional synchronies in various hierarchic levels of complexity ultimately harmonized within a global synchrony. This architecture is sometimes referred to as a UMC, or dynamic core as mentioned previously [22] [59] . Metastability in reference to cognitive neuroscience describes the neural activity of coordinated, global integration of independent functional modules that retain their autonomy while still being a part of macro operations [92] [93] [94] . In this metastable mode of function consisting of the co-existence of independence and cooperation, information is created and then percolated throughout the various dimensions of dynamic bioelectric operations across various neural and macroscopic assemblies [95] [96]

Metastability helps solves the mystery of how diverse and distributed brain activities can give rise to a single integrated experience. Such neural activity of consciousness is metastable because involved brain regions perform their own innate tasks while still coordinating together to create a larger, more abstract architecture [97] . This characteristic may allow for the non-linear dynamics of global bioelectric frameworks which switch dynamically from state to state, each bioelectric state transition arising from a reconfiguration of the underlying neural network configuration [98] [99] . Metastable brain states are like winner-less competitions, each unique state being outside of natural equilibrium but only dominating global activity for a period of time (quasi-equilibrium) [100] . Each quasi-stable state when reaching the point of instability quickly shifts to other quasi-stable states during “rapid transition processes” [101] . Operating close to points of instability allows for rapid switching between states [98] . The brain at rest has been found to have to most amount of network switching between unique metastable states [102] .

There are three general dimensions of bioelectric activity from microscopic to macroscopic. Macroscopic activity is suggested to be responsible for the integrated experience and can influence the micro/mesoscopic while also ultimately being composed of micro/mesoscopic activity [32] [103] . Neural and non-neural cells microscopically communicate electrical membrane potential events to adjacent cells via synaptic communications [104] , electrical coupling via gap junctions [105] , ephaptic coupling via local electric fields [106] , and dynamic interactions of voltage-gated ion channels [107] . Mesoscopic brain dynamics occur between groups of neurons within cortical areas. They occur via synaptic and electric field interactions and lead to synchronized firing patterns that can result in synchronization of firing patterns with other cortical areas [32] [108] . This gives rise to large-amplitude oscillations which can be observed outside the scalp using electroencephalography [108] . Such interactions between distal brain areas are referred to as macroscopic oscillations which may form synchronized feedback loops that occur most often in the thalamocortical system [69] . At this level, a greater level of orderly complexity and abstraction emerges as coherence among all or many mesoscopic networks is formed [1] .

The binding of mesoscopic modules unties the sensory and cognitive frameworks into a global harmony and thus allows for the integrated consciousness experience [1] [32] . The DST and OAT describe such global macroscopic oscillations as the highest level and complexity of the unified bioelectric structure responsible for the integrated experience as a harmonic amalgamation of mesoscopic and thus microscopic activity among independent modules [11] [32] . The DST extends this bioelectric architecture from only the brain as described by OAT, to the peripheral sensory organs [8] [38] [109] . Synchronous interactions temporarily occur between specialized assemblies responsible for certain perceptual qualities [110] . For instance, neural assemblies responsible for depth perception synchronize with those responsible for brightness leading to perceived changes in brightness to alter the perception of depth [32] . The integrated experience is likely formed when synchronies between various modules synchronize with other oscillatory functions leading to a more abstract and higher level order which can be global [32] . Therefore, this vast complexity of bioelectrical operations that occur at multiple levels from the basic membrane activity of the cell to global oscillations may create the physiological architecture for a “virtual” reality of consciousness with the lower levels of membrane potential activity creating the underlying unconscious fabric by providing a fundamental substrate for mesoscopic and thus macroscopic harmonic activity.

Edelman has described two types of consciousness, a basic sensory consciousness and a higher or secondary consciousness. Sensory consciousness is the primary consciousness which consists solely of sensory qualia bound to time and space without any sense of past or future [111] . This primary consciousness occurs in animals with humans additionally possessing advanced metacognition allowing us to have higher consciousness and be “conscious of being conscious” [59] . Phenomenal consciousness and its qualia intuitively seem and are referred to largely as inherently non-physical [1] [112] [113] [114] [115] . Pondering how an experience, although emerging from the material, chemical, and electrical operations of neurons could be physical leads nowhere fast [116] . Assuming that conscious experience is non-physical and that distributed bioelectric operations are isomorphic to consciousness, there arises a mystery on the nature of such “higher” or “meta” consciousness. The fact that we are cognitively aware that we are conscious strongly suggests such awareness is coded into our physical brains. Similar to other problems arising from the clash of physicalism and non-physical qualia, if the qualia of phenomenal experience are truly non-physical, then there exists an “interface” problem of how the physical system of the brain could know, understand, and be cognitively aware of something non-physical. Edelman suggests syntactical language allows for such “meta-consciousness” [59] , however, this explanation is very unsatisfactory when looking at the interface problem from a physical systems perspective.

Even when external sensory stimuli cease, the experiential frameworks of the respective sensations most often remain idling in consciousness. For instance, when entering a completely lightless room, you do not cease to see, however, you see blackness. Those without such a visual framework developed over years of experience-based learning such as in the case of the congenitally blind lack any experience of visual imagery whatsoever and do not “see” darkness [117] . People born blind have no first-hand understanding of what it is like to have vision, and if they somehow acquired working retinas later in life, the brains of those congenitally blind patients would receive a flood of visual stimuli that they are not prepared to handle [118] . However, due to the brain’s amazing ability to identify informational patterns and dynamic neuroplastic ability to restructure existing cortex with a different active role, those congenitally blind patients with restored vision can learn to truly see, even without a retina or occipital lobe (potentially all) [119] [120] . By mounting a camera on their shoulder and a stimulus converting, pixelated array/screen of vibrating units (each unit vibrating in intensity relative to the brightness of its pixel location in the 2D visual image) on their tongues or backs, their brains can learn to transform the tactile information into a visual experience [119] . Cameras can also be used to turn visual images into soundscapes which can be experienced as visual when enough practice has taken place [121] .

In these successful “sensory substitution” methods, it appears that the unique organization of information in stimuli is identified and formatted into an appropriate sensory framework by the brain [122] . These insights indicate the “blueprints” for sensory frameworks lie not in their cortical locations or sensory receptor anatomy, but in an operational, bioelectric structure differentiated not only by physical signal properties of the operations among distributed assemblies, but in the information processing system they create. Depending on their metastable bioelectric architecture they produce a unique phenomenal quality from the variety of sensory modalities. Thus, any new frameworks that would be developed could be integrated into a UMC naturally by the brain, providing the potential for future neuroengineering efforts that would allow people to consciously see things like x-rays, other frequencies of the electromagnetic spectrum, or truly anything which could be sensed with a device and transduced into equivalent neural activity. This could be implemented by the “sensory substitution” described (camera-to-tongue) [119] or perhaps by direct input to the appropriate thalamic nuclei.

7. The Top-Down Domination of Perception

We have discussed how our experience of reality is truly an “informed hallucination”, a virtual simulation generated within. Furthermore, this experience is likely dominated by perceptions and predictions largely formulated within the brain [11] . Of the vast amount of sensory stimuli bombarding our many sensory organs at any given moment, an estimated 99% of the data is discarded [123] . Our brains simply do not possess the computational power to process such an immense spectrum and quantity of sensory stimuli and have it all presented to conscious awareness [124] . The DST suggests top-down predictions transported via bioelectric synchrony [60] (also the substrate of experience) dominate in generating the information embedded into the subconscious 3D matrix or default space [11] . By integrating cognitive predictions with incoming sensory stimuli, computational demands can be greatly decreased [60] [124] .

Top-down predictions derived from current context (current state of world simulation), attention, memory, biases, past experiences, higher cognitive functions, and even genetics [125] likely modify, filter, and amplify transduced stimuli [126] . The DST asserts the externalized simulation that we experience day to day is the most crucial source of expectations (particularly expectations of the environment such as localizations of objects) which allow for near immediate integration of incoming predicted stimuli into the continually maintained world simulation [8] . Each moment of this world simulation provides a means to derive expectations about the next [11] .

Mechanisms for top-down predication are vastly important in reducing surprise, uncertainty, and time and energy expenditures while facilitating interactions with external stimuli [124] . The accurate prediction of the external world from the internal template is not an genetically innate function. Experience-based mapping and development of sensory modalities to qualities and concepts of the real world (movement, occlusion, etc.) must take place before accurate predictions of the world can be integrated with incoming stimuli and experienced as such [124] . By integrating stored knowledge, current context, and higher cognitive functions with sensory input, there is an immense reduction in the necessity of considering large numbers of external causes for sensory events which enables quicker [127] and more accurate [128] conscious interpretation of such events [124] .

If sensory experience were solely a bottom-up process, many ambiguous properties of a stimulus could not be resolved as often they can only be resolved by inferring properties through context derived from previous experiences [129] . Expectations are thought to originate at higher cortical sites and project to lower cortical sites as well as all the way back to the thalamus [126] . Indeed, top-down projections from higher-level cortical regions to lower-level ones are abundant, most notably in the visual and somatosensory systems [130] [131] (Figure 4). Although traditionally neglected, prodigious feedback connections exist in both systems extending to thalamus, brainstem, and even spinal cord (somatosensory), actually outnumbering feedforward connections [131] [132] .

While such top-down effects may be thought of as an unconscious cognitive activity, there is indeed an intimate relationship between top-down mechanisms and consciousness. Top-down expectations increase the speed of conscious access to relevant perceptual stimuli [133] [134] and may boost otherwise unconscious stimuli into awareness [126] . This intimate connection is deepened when considering the fact that the substrate or mechanisms from which consciousness emerges as well as of top-down effect are described very similarly by prominent models, both consisting of reentrancy [135] [126] , bioelectric synchrony [59] [137] , and feedback [60] [138] . Information reaching conscious awareness is thought to trigger the feedback, macroscopic reentrant activity, and any-to-many “broadcasting” needed for top-down effect and which are most readily implemented by the thalamocortical system [65] [126] . Indeed, stimuli than confirm our expectations are more likely to enter awareness [126] , possibly by amplifying the stimulus or by sharpening neural representations of it [139] . It is likely that active implementations of top-down predictions require conscious awareness of them [126] .

In addition to academic research, numerous self-observations and neurological conditions reveal the nature of the top-down prevalence of perception. For instance, those suffering from phantom limb syndrome experience possessing a “ghost limb”, or body part that once existed but was lost due to an amputation or accident [140] . These sensations arise from topographically organized, somatotopic maps of the body in the somatosensory cortex [140] . This condition illustrates how what we experience is not dependent on what signals are sent from the sensory receptors, but derived more so from the contents of the mind [141] . An experiment that can be performed at home, the “rubber hand illusion”, further demonstrates how even the unified sense of self is a construction of the mind. In this illusion, focusing on an artificial hand being stroked synchronously with one’s concealed hand leads the participant to experience the artificial hand as being their real hand [142] . Top-down phenomenona can be so intriguing that they have often become a focus of worldwide popular attention via the media. For instance, an audio clip that went viral due to top-down differences among people was perceived significantly differently to around half of listeners than to the other half depending on how their brains interpret the various frequencies in the audio based on experience and expectations [143] . Some perceived hearing the word “laurel”, while others heard “yanny”, and by intentionally expecting to hear one or the other, many listeners can choose which one they hear.

8. An Organizational Hierarchy

Hierarchy is a fundamental concept of modern theories of brain function [144] . The UMC and neural activity in general have been proposed by a variety of author’s to be composed of a variety of dimensions of hierarchies [145] including the micro-to-macroscopic bioelectric hierarchy discussed and hierarchies of neural pattern recognizers [146] , parallel loops, oscillators [145] , anatomical layout [147] , and fractal or nested network modules [109] [148] [149] . In addition to these, a frequency-based hierarchy likely exists for non-linear bioelectric activity [12] . As mentioned, we have asserted that ultra-slow frequencies of micro-to-macroscopic oscillations are a foundation for a UMC isomorphic to the virtual foundation (a 3D matrix) of consciousness [13] . This is derived from the idea that neural activity from which mind emerges (a UMC) is self-organized so that slower frequency activity underlies faster frequency activity. Modern research supports this idea that bioelectric oscillatory activities are hierarchically organized so that the signal properties of each frequency band (alpha, gamma, etc.) are modulated, entrained, locked with, and grouped by the lower frequency oscillations [34] [67] [150] [151] [152] [153] (Figure 2). We have proposed that bioelectric activity (from which mind emerges) in the form of oscillations occur in frequency-based layers and that the lower layers support activity of the higher layers [12] (Figure 3).

The most basic layer we have described consists of ultra-slow to slow, intrinsic activity of neural and non-neural activity. The non-neural activity will be discussed in the next section. The neural component consists largely of activity within the default mode network ( DMN ) which has an importance in supporting higher activity illustrated by the relative cost of its activity in terms of brain

energy consumption [12] . The majority of brain energy consumption is attributed to this intrinsic activity [154] . The DMN being a key component of such an essential layer underlying consciousness is supported by research correlating DMN connectivity to level of consciousness in brain-damaged patients [53] , behavioral signs of awareness [155] , and some meditative experiences [156] . We assert that intrinsic brain activity uses so much energy due to its function in maintaining the neural framework that founds the subconscious 3D virtual matrix necessary for conscious perceptions [12] . In addition, intrinsic activity from the DMN likely models our experience of being a unified self, centered in space in direct relation to the subconscious 3D virtual space [85] . This intrinsic activity modulates, influences, and supports high-level oscillatory processes involved in cognition [157] , memory [158] , learning [159] , and other functions of mind, unifying them all by binding them to the virtual space framework.

Baars explained how “a serial, integrated and very limited stream of consciousness emerges from a nervous system that is mostly unconscious, distributed, parallel and of enormous capacity” [160] . Thus, unconscious activity is at the bottom of multiple dimensions of hierarchy. Understanding the difference between the hierarchy of unconscious to conscious physiological activity would greatly advance the knowledge of what consciousness really is, and so this understanding is a prime focus in cognition research [161] [162] [163] . Eagleman has thoroughly explored the vast domination of the unconscious mind in our behaviors and thoughts, describing the conscious mind as “a stowaway on a transatlantic steam ship, taking credit for the journey without acknowledging the massive engineering underfoot” [45] . The Fingelkurts have described the lowest layer of the brain-mind hierarchy (micro-to-macro) which supports the upper layers as the physical, molecular operations of neurons which may better be

described as nonconscious [32] , as this layer lacks any experiential ontology [164] . They describe how at the next brain-mind layer the conscious/unconscious border exists. This is the layer of transient functional neural assemblies which support basic cognitive operations [32] . On top of this hierarchy exists the layer producing reflective consciousness, which is the synchronization of complex macro operations into the greatest level of complexity and abstraction [1] [165] .

9. From Embodied Cognition to Embodied Consciousness

Embodied cognition is the “radical” field of hypotheses that the brain is not the sole cognitive resource and that our bodies play a significant role in our psychologies [166] . Although this approach is a traditional, holistic aspect of eastern medicine, it is relatively new to cognitive science and is considered radical because it rejects the “mind as a computer” metaphor [167] . In embodied cognitive science, many models of psychological and biological systems consider the brain, mind, and body as a single entity in a holistic manner. Although embodied cognition is not unified in its established definitions and research goals [168] , a general view is that the body not only affects the mind, but the mind affects the body via dynamic interactions [169] . Although speculative we extend this idea to consciousness, propounding the body plays a significant role in the emergence of consciousness. Although there is not sufficient evidence to fully consider this concept a principle as of yet, we feel strongly enough about the importance of the body and promoting research into it that we have included it.

A growing body of research shows that the cognitive system is highly dependent on sensory and motor functions of the body, suggesting that sensing and acting should be considered an essential aspect of higher-level cognition [170] . For example, holding a warm cup of coffee versus a cold one leads participants to judge a new acquaintance as more trustworthy after a brief interaction [171] . Thinking about the future caused participants to lean slightly forward, while thinking about the past caused them to lean slightly backward [172] . Force laughter and smiling substantially improves mood in participants [173] . Although these studies are based on primary experiences, further research into the physiology of brain-body unity will likely ground the embodiment hypothesis in more physical, biological science. The DST has extended this embodiment science to include a greater physiological and psychological perspective on consciousness, further including the sensory organs and respiratory and cardiovascular systems as crucial components and influencers of mind which have received little attention in the embodiment sciences literature.

Lateral Inhibition has been well researched and known to be a crucial mechanism in many types of sensory perception [174] [76] [176] [177] . We have proposed how a synchrony among the cortex and sensory organs allows the body and brain to conglomerate together as a single UMC which thus allows an extension of top-down effects and information to the sensory organs [109] . According to this embodied perspective, sensory organs not only initiate transduction of incoming external stimuli, but are an active component of physiologic processes isomorphic to the perceptual experiences that occur [18] . We propose this occurs via a process best described “lateral inhibition across abstract dimensions” [178] . Although lateral inhibition is commonly referenced in a local, spatial sense, we refer to it in a functional sense. This refers to interactions that occur at a distance between the cortex and sensory organs but remain functionally connected through oscillatory synchronization. Through this type of lateral inhibition or even amplification, sensory stimuli can become amplified or filtered based on the current state of the internal world simulation which allows for expectations about incoming stimuli to be formed [18] . Top-down amplification has been studied showing that there can be amplification at 100,000 times greater than the result of stimuli alone [179] .

According to the DST, membrane potential oscillations (MPOs) between the thalamus and sensory organs along their afferent fibers are integrated with cortical activity by the thalamus, providing a medium for top-down feedback [18] . This hypothesis is supported in part by the fact that prodigious top-down projections to the thalamus and brainstem from (somato)sensory cortices actually outnumber bottom-up projections (at least 3:1) [131] [180] [181] and that these descending projections in some cases extend to the sensory organs such as the retina [181] . MPOs have also been observed on afferent fibers, modulating sensory signals to the brain [182] . Projections from the retina to the lateral geniculate nucleus, which is the thalamic relay center from the retina to the occipital lobe [183] , have been shown to oscillate with such nucleus via which synchrony is further created with the visual and association cortices [184] [185] .

The top-down feedback to the thalamus and brainstem is fundamental in implementing sensory predictions [60] [181] but traditionally has been neglected [131] . Thus, we have thus extended these well-known projections to the thalamus to the sensory organs themselves via bioelectric synchrony (Figure 4). Sensory organs may thus be more influenced by the thalamocortical system than by actual external stimuli. For example, if one is walking in the woods and comes across a stick that looks like a snake, one may briefly see an actual snake due to the emotionally strong top-down indication of seeing one. In this brief moment, before the realization occurs, the “image” of a snake may exist on the retina itself even though the true external stimulus is that of a stick. This is because the top-down effects are strong enough to cause the retinal cells to signal each “pixel” of an internally generated, 3D image.

As mentioned in the thalamus principle, Edelman asserts that conscious sensory perception emerges from coherent synchrony among multiple distal cortical areas maintained by reentrant activity among the thalamocortical network [59] . The Fingelkurts describe sensory consciousness as originating from “operational modules” of bioelectric synchronies between functional brain modules that integrate together forming a global metastable continuum responsible for the integrated and unified experience [1] [32] [93] . The DST, however, extends these concepts to the peripheral nervous system by describing how the thalamus not only forms such feedback loops with the cortex but also with sensory organs of the body via MPOs and integrates these loops together [109] . We have deemed these reentrant loops with the body “thalamosomatic loops”.

MPOs are ideally suited to provide efferent feedback to sensory receptors as they can co-occur on afferent fibers and provide a medium for bioelectric synchronization [186] . MPOs have been shown to play key roles in perceptual and other signal processing [187] [188] as well as encoding information [189] . Neurons may adjust their firing patterns based on MPOs [188] , enabling very precise control of neuronal firing [186] . MPOs are also suggested to work as a priming

mechanism, priming synapses and networks to receive certain input based on expectations [60] . According to this top-down MPO model, in the case of vision, the many modules of the visual cortex that process color, distance, space, and motion would be appropriately synchronized with the photoreceptors of the retina [18] . They would not directly synchronized, but the thalamus would act as the intermediary or hub between the central and peripheral nervous systems, integrating diverse activity from the cortex and projecting the top-down signals to the respective sensory organs. Through this oscillatory synchronization, the sensory receptors can expect certain stimuli to fall upon them, and can begin to process incoming stimuli at the site of the receptors facilitating near immediate conscious awareness of external sensation [18] .

We and others have recognized respiration as an influencer and even fundamental component of the dynamic bioelectric activity occurring throughout the brain [151] [190] [191] [192] [193] (and potentially body) [8] . In the hierarchical model of the DST described, the lowest layer involves intrinsic neural and cardiorespiratory activity that while unconscious, are vital to the higher order functional activity that gives rise to consciousness [12] . The low frequency oscillations of breathing have been thought to drive a broad range of oscillations throughout the brain [151] as well as modulate cortical functions, including emotional and cognitive processes [194] . Local field potential oscillations reveal respiration-entrained rhythms that do not have standard oscillatory properties [195] . These rhythms have been shown to be more widespread than previously believed and ourselves and other authors assert that they represent a global coherence mechanism [151] .

Respiration-entrained rhythms are suggested to exist in order to sustain and maintain unification and coherence among neuronal oscillatory activity, exerting significant influence on movement, sensation, and cognitive processes [191] . Thus, the main mechanism by which the body influences the brain is via the modulation of neural oscillatory synchronization by sensory inputs throughout the body [191] . The DST takes this further by asserting oscillatory synchronization throughout the body as well as the brain [11] , and suggests that respiration may even dynamically modulate neuronal membrane potentials [196] . Motor activity has been tied to respiration through demonstration that handgrip force is significantly stronger during forced expiration than during forced inspiration [197] , and eye movements have been shown to be phase-locked to respiration [198] . The influence on sensation by respiration has been substantiated through research on visual and auditory signal detection, revealing that the threshold for signal detection is higher during inspiration compared to expiration [199] . In addition, during controlled breathing, reaction times are significantly increased during expiration compared to inspiration [192] [200] .

Due to this significant influence of breathing on neural activity, we have proposed how we may regulate this activity globally by regulating our breathing patterns [201] . This is the foundation of our assertion that meditative breathing exercises may be more overall effective in treating emotional disorders such as anxiety and depression than pharmaceutical approaches [201] . There is a strong correlative relationship between respiration rates and autonomic activity, with higher respiration rates stimulating the sympathetic [202] and lower rates stimulating the parasympathetic tone [203] . Research into how controlled slow breathing optimizes homeostatic parameters and promotes health and longevity [203] may reveal integral, vital activities of the unified biological system that is our brain and body.

The heart may also influence the mind via cardiorespiratory synchronization which is a coupling between the heart beat and the respiratory phase often occurring during sleep or anesthesia, and while it has been under investigation for twenty years, no clear clinical implications have been substantiated [204] . High levels of cardiorespiratory synchronization occurring during meditative breathing practices may play a role in the resulting modulation of the autonomic system, amygdala activity, and the relaxation response [205] . Stress is associated with a sympathetic response and a decrease in cardiorespiratory synchronization

[206] . The hyper-sympathetic state is also correlated with a plethora of chronic diseases such as heart disease and even obesity [207] . Modern lifestyles and goals have been proposed to be behind a widespread and persisting sympathetic over-activation due to an evolutionary mismatch between our predictable, pre-history, tribal lifestyles and the modern hectic lifestyles we live today [208] [209] . By regulating our breathing, we may be able to reduce the ill effects of disrupted sympathovagal balance, enhance poor autonomic reactivity to stress [203] , and control otherwise unconscious bodily processes [202] (Figure 5).

10. Conclusion

Consciousness is proposed to be an emergent property from the complex biological systems that we are. The perspective on which concepts can be considered principles of consciousness has been derived from agreements among top models and their top insights, along with our own hypotheses. This perspective is largely through the lens of the Default Space Theory which is novel and yet can be understood as an expansion of other powerful metastable models such as the Global Workspace Theory and the Operational Architectonics Theory. It is distinct from other metastable models of consciousness in its embodied architecture which extends the unified metastable continuum to the body, not solely the brain. The foundations of human consciousness we have explored may likely be answers to the “easy” or “real” problems of conscious. Only when we solve the “real problem” of consciousness, how we can account for consciousness in terms of biological mechanisms, can we begin to ponder the “hard problem”, the physical nature of how conscious experiences arise solely from the physics of chemistry, electromagnetism, and kinetics that are the basic mechanisms of the body and brain. Through understanding principles of consciousness, modern medicine may make greater strides in developing therapies for cognitive medical conditions and cognitive/computer scientists may even ignite a new age of artificial intelligence.

Acknowledgements

Funding has been provided by Charitable Medical Healthcare Foundation.

Authors’ Contribution

Theory developed by RJ with some writing with the majority of the manuscript written by CB.

Funding

Funding provided by Charitable Medical Healthcare Foundation.

Conflicts of Interest

The authors declare no conflict of interest.

Abbreviations

Default Space Theory (DST), Integrated Information Theory (IIT), Operation Architectonics Theory (OAT), Autonomic Nervous System (ANS), Unified Metastable Continuum (UMS), Default Mode Network ( DMN ), Membrane Potential Oscillation (MPO)

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