<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    odem
   </journal-id>
   <journal-title-group>
    <journal-title>
     Occupational Diseases and Environmental Medicine
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2333-3561
   </issn>
   <issn publication-format="print">
    2333-357X
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/odem.2025.132005
   </article-id>
   <article-id pub-id-type="publisher-id">
    odem-142761
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Medicine 
     </subject>
     <subject>
       Healthcare
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Prevalence and Factors Associated with High Blood Pressure in Mining Workers in Franceville, Gabon in the Year 2023
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Martial Hervé
      </surname>
      <given-names>
       Ekomy
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Alda Marcelle
      </surname>
      <given-names>
       Ngoubadjambo
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Patrice
      </surname>
      <given-names>
       Landimi
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Franck Léonard Nguema
      </surname>
      <given-names>
       Ezengue
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Laurent Irwin
      </surname>
      <given-names>
       Makosso
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff4"> 
      <sup>4</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Herman
      </surname>
      <given-names>
       Begouabe
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff5"> 
      <sup>5</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Laetitia Pauline Abang
      </surname>
      <given-names>
       Ekouaghe
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff6"> 
      <sup>6</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Bekale Ndong
      </surname>
      <given-names>
       David
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Armel
      </surname>
      <given-names>
       Kinga
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff7"> 
      <sup>7</sup>
     </xref> 
     <xref ref-type="aff" rid="aff8"> 
      <sup>8</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Cédric Sima
      </surname>
      <given-names>
       Obiang
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff5"> 
      <sup>5</sup>
     </xref> 
     <xref ref-type="aff" rid="aff9"> 
      <sup>9</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Léon Jules Owona
      </surname>
      <given-names>
       Manga
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff10"> 
      <sup>10</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Mor
      </surname>
      <given-names>
       Ndiaye
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff11"> 
      <sup>11</sup>
     </xref>
    </contrib>
   </contrib-group> 
   <aff id="aff1">
    <addr-line>
     aDepartment of Occupational Health, Polyclinic Haut-Ogooué, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff2">
    <addr-line>
     aHaemodialysis Centre, Amissa Bongo University Hospital, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff3">
    <addr-line>
     aDepartment of Occupational Health, Health Sciences University, Libreville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff4">
    <addr-line>
     aDepartment of Occupational Health, Clinic COMILOG, Moanda, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff5">
    <addr-line>
     aDepartment of Biology, Polyclinic Haut-Ogooué, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff6">
    <addr-line>
     aDepartment of Paediatrics, Health Sciences University, Libreville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff7">
    <addr-line>
     aDepartment of Cardiology, Polyclinic Haut-Ogooué, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff8">
    <addr-line>
     aDepartment de Cardiology, Amissa Bongo University Hospital, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff9">
    <addr-line>
     aLaboratory of Research in Biochemistry, Masuku University of Sciences and Technology, Franceville, Gabon
    </addr-line> 
   </aff> 
   <aff id="aff10">
    <addr-line>
     aDepartment of Public Health, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon, Douala
    </addr-line> 
   </aff> 
   <aff id="aff11">
    <addr-line>
     aDepartment of Occupational Health and Safety and Environment, University of Cheikh Anta Diop of Dakar, Dakar, Senegal
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     06
    </day> 
    <month>
     05
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    13
   </volume> 
   <issue>
    02
   </issue>
   <fpage>
    61
   </fpage>
   <lpage>
    75
   </lpage>
   <history>
    <date date-type="received">
     <day>
      18,
     </day>
     <month>
      April
     </month>
     <year>
      2025
     </year>
    </date>
    <date date-type="published">
     <day>
      20,
     </day>
     <month>
      April
     </month>
     <year>
      2025
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      20,
     </day>
     <month>
      May
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    <b>Aim of </b>
    <b>Study</b>: To determine the prevalence and the factors associated with arterial hypertension (AH) among workers in the mines of Franceville, Gabon, in the year 2023. 
    <b>Patients and Methods</b>: We conducted a cross-sectional, analytical study at the Polyclinique du Haut Ogooué (PHO) in Franceville, Gabon, between 1 January and 31 December 2023. Employees of a mining company were selected by purposive sampling. Socioprofessional, clinical and biological data were collected using an anonymous questionnaire. The statistical study was performed using Epi Info 7.2.6 software. Factors associated with the occurrence of hypertension were determined by logistic regression at the α = 7% level and at the p ˂ 5% significance level. 
    <b>Results</b>: We included 288 participants, with a male predominance (86.46%). The median age was 39 years [22 - 93 years]. Most participants were blue-collar workers (49.31%), and the majority worked night shifts (71.18%). More than half of the participants were overweight or obese (60.42%). The prevalence of hypertension was 44.79%. Multivariate logistic regression identified two factors associated with incident hypertension: a history of diabetes (OR 36.42 [4.07 - 325.89], p = 0.00) and alcohol consumption (OR 1.99 [1.21 - 3.31], p = 0.007). 
    <b>Conclusion</b>: The study revealed a high prevalence of hypertension and two associated predictive factors in this mining company. It is therefore necessary to set up an occupational health department within the company. This will contribute to better screening, prevention and health promotion strategies.
   </abstract>
   <kwd-group> 
    <kwd>
     Arterial Hypertension
    </kwd> 
    <kwd>
      Mine
    </kwd> 
    <kwd>
      Franceville
    </kwd> 
    <kwd>
      Prevalence
    </kwd> 
    <kwd>
      Gabon
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>The fight against non-communicable diseases is an important issue in the general population and in the workplace. Studies have highlighted the occupational risks that can influence the onset of cardiovascular disease, with hypertension being the most common pathology <xref ref-type="bibr" rid="scirp.142761-1">
     [1]
    </xref>. It remains a public health problem in sub-Saharan Africa because of its prevalence and its association with cardiovascular and renal disease <xref ref-type="bibr" rid="scirp.142761-2">
     [2]
    </xref> <xref ref-type="bibr" rid="scirp.142761-3">
     [3]
    </xref>. In 2010, it affected 1.39 billion adults worldwide, three-quarters of whom lived in developing countries <xref ref-type="bibr" rid="scirp.142761-4">
     [4]
    </xref>. As a result of its morbidity and mortality, hypertension leads to an increase in sickness absence, permanent disability, occupational accidents, unemployment and a significant loss of productivity for the company and, most importantly, for the employee <xref ref-type="bibr" rid="scirp.142761-5">
     [5]
    </xref>. Studies of hypertension in the workplace have shown high prevalence rates <xref ref-type="bibr" rid="scirp.142761-3">
     [3]
    </xref> <xref ref-type="bibr" rid="scirp.142761-6">
     [6]
    </xref>. Other studies conducted in Africa, Europe, Canada and the United States have also confirmed the high prevalence of hypertension among workers, suggesting a relationship between the onset of hypertension and work <xref ref-type="bibr" rid="scirp.142761-7">
     [7]
    </xref>-<xref ref-type="bibr" rid="scirp.142761-12">
     [12]
    </xref>. This association is all the more pronounced as studies have highlighted the impact of work activities and the work environment on the development of hypertension, particularly occupational stress <xref ref-type="bibr" rid="scirp.142761-13">
     [13]
    </xref> <xref ref-type="bibr" rid="scirp.142761-14">
     [14]
    </xref>, shift work <xref ref-type="bibr" rid="scirp.142761-15">
     [15]
    </xref> and occupational noise <xref ref-type="bibr" rid="scirp.142761-16">
     [16]
    </xref>. Studies have also highlighted the link between socio-demographic characteristics (such as age) and workers’ habits and lifestyles (such as obesity, excessive salt consumption, alcohol consumption and smoking) and the onset of hypertension <xref ref-type="bibr" rid="scirp.142761-15">
     [15]
    </xref> <xref ref-type="bibr" rid="scirp.142761-17">
     [17]
    </xref> <xref ref-type="bibr" rid="scirp.142761-18">
     [18]
    </xref>. This research confirms the need to pay special attention to this pathology in the workplace. This condition also affects the occupational environment in Gabon to varying degrees depending on the field of activity. Studies on the prevalence of hypertension in the workplace have found the following rates: 45.2% in hospitals <xref ref-type="bibr" rid="scirp.142761-19">
     [19]
    </xref>; between 13.48% and 37% in the oil industry <xref ref-type="bibr" rid="scirp.142761-20">
     [20]
    </xref> <xref ref-type="bibr" rid="scirp.142761-21">
     [21]
    </xref>; 39.9% in mining <xref ref-type="bibr" rid="scirp.142761-6">
     [6]
    </xref>; and 35.2% in construction <xref ref-type="bibr" rid="scirp.142761-22">
     [22]
    </xref>. These studies report an association between the onset of hypertension and age, sex, alcohol consumption, smoking, and body mass index <xref ref-type="bibr" rid="scirp.142761-6">
     [6]
    </xref> <xref ref-type="bibr" rid="scirp.142761-22">
     [22]
    </xref>. Understanding these risk factors is essential for developing effective preventive strategies and combatting hypertension. However, very few studies have been carried out in the mining sector, despite it being a fairly important area of activity in the country. To strengthen the prevention and medical surveillance of workers in this sector, we investigated whether other risk factors might be associated with the onset of hypertension, such as diabetes, exposure to noise and night shift work. The present study was conducted for this purpose. It aimed to estimate the prevalence of hypertension and identify the associated factors in mine workers in Franceville, Gabon.</p>
  </sec><sec id="s2">
   <title>2. Patients and Methods</title>
   <sec id="s2_1">
    <title>2.1. Type, Duration and Place of Study</title>
    <p>The study was cross-sectional and analytical. It took place over 12 months, from 1 January to 31 December 2023, at the Polyclinic du Haut Ogooué (PHO) in Franceville. It was conducted during the periodic medical check-ups of workers at a mining company located three kilometres from Franceville, the capital of the Haut-Ogooué province in south-eastern Gabon. The company mines manganese in open pits and operates continuously. Eight-hour shifts (morning, evening and night) are standard at the sites. The company employed 321 workers to carry out various activities. The PHO Occupational Health Service was responsible for conducting the workers’ periodic medical examinations.</p>
   </sec>
   <sec id="s2_2">
    <title>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>2.2. Study Population and Sample Size</title>
    <p>The study population consisted of all employees of the mining company who underwent a periodic medical examination at the PHO in 2023.</p>
    <p>The minimum sample size for the study was calculated using Cochran’s formula <xref ref-type="bibr" rid="scirp.142761-23">
      [23]
     </xref>.</p>
    <p>
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     </math></p>
    <p>A flat prevalence of 50% and an error threshold of α = 7%.</p>
    <p>Assuming a non-response rate of 10%.</p>
    <p>Where ns = sample size to adjust for non-response</p>
    <p>0.90 = the expected response rate is assumed to be 90%.</p>
    <p>ns = n/0.90</p>
    <p>ns = 196/0.90</p>
    <p>ns = 217.77, i.e., approximately 218 workers for the minimum sample size required for our study.</p>
    <p>We used an exhaustive sample in our study.</p>
    <p>All voluntary workers from the mining company who agreed to participate in the study and gave their consent were included. Absent workers and those who had not completed their medical examinations at the PHO in 2023 were excluded from the study.</p>
   </sec>
   <sec id="s2_3">
    <title>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>2.3. Study Variables</title>
    <p>The dependent variable of the study was arterial hypertension and the independent variables were as follows:</p>
   </sec>
   <sec id="s2_4">
    <title>2.4. Collecting Data</title>
    <p>Data was collected using an anonymous questionnaire that included socio-professional, clinical, biological and environmental data. The questionnaire has been validated by the Haut Ogooué Provincial Ethics Committee. It was inspired by the STEPS questionnaire developed by the World Health Organization (WHO).</p>
    <p>On the day of the medical examination, the workers arrived at the PHO on an empty stomach in the morning, as scheduled by the human resources department of the mining company. At the reception desk, they provided their identity and telephone number, after which the computer automatically assigned them an identifier. They were then taken to the room for medical examinations. Each worker was informed about the survey, their anonymity, the confidentiality of the data, and their right to refuse to participate in the study. After the parameters had been taken, the research team administered the questionnaire to all workers who had given verbal consent. The workers then underwent clinical examinations, imaging tests and biological testing.</p>
    <p>In the sampling room, an experienced biologist took blood samples using elbow venipuncture. The samples were collected in tubes containing:</p>
   </sec>
   <sec id="s2_5">
    <title>2.5. Instruments Used to Measure the Study</title>
   </sec>
   <sec id="s2_6">
    <title>2.6. Operational Definitions</title>
   </sec>
   <sec id="s2_7">
    <title>2.7. Data Analysis</title>
    <p>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>The data was analysed using Epi Info 7.2.6 software. The results were presented in descriptive and analytical form according to the type of variable. Analysis was performed using Fisher’s exact test (qualitative variables) and the non-parametric Kruskal-Wallis test (qualitative variables), which allowed comparisons between groups at the threshold of α = 7%, p &lt; 5%. Logistic regression was used to search for associations between arterial hypertension and other variables. This was performed at an inclusion threshold of 0.2.</p>
   </sec>
   <sec id="s2_8">
    <title>2.8. Ethical Approval</title>
    <p>An anonymous questionnaire was used. Participants gave their consent before taking part in the study. The work described does not involve experiments on patients, human subjects or animals. All the tenets of the Declaration of Helsinki concerning human subjects in research were followed during data collection. Ethical approval was obtained from the Regional Ethics Committee of the Province of Haut-Ogooué (PROT N˚14/2023/MSAS/DRSSEF).</p>
   </sec>
  </sec><sec id="s3">
   <title>3. Results</title>
   <sec id="s3_1">
    <title>3.1. Socio-Professional Characteristics of the Participants</title>
    <p>Of the 295 workers who underwent a medical examination at the PHO in 2023, a total of 288 were included in the study (97.63%), of whom 249 (86.46%) were men. The sex ratio was 6.38 (M/F). The mean age was 39 years [Range 22 - 93 years]. Half of the respondents were blue-collar workers (49.31%) and the vast majority had been with the company for less than 10 years (93.4%). (<xref ref-type="table" rid="table1">
      Table 1
     </xref>).</p>
    <table-wrap id="table1">
     <label>
      <xref ref-type="table" rid="table1">
       Table 1
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.142761-"></xref>Table 1. Socio-professional characteristics of the subjects surveyed.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="48.91%"><p style="text-align:left">Variables</p></td> 
       <td class="custom-bottom-td aleft" width="51.09%"><p style="text-align:left">n = 288</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Age (Years)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Median age (IIQ)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">39 (22 - 93)</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&lt;=30 (n = 31) </p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">10.6%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&gt;30 - 50 (n = 236)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">81.94%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&gt;50 (n = 21)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">7.30%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Sex </p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Woman (n = 39)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">13.54%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Man (n = 249)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">86.46%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Job category</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Foreman (n = 39)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">13.54%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Framework (n = 27)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">9.38%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Management (n = 4)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">1.39%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Worker (n = 142)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">49.30%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Intern (n = 28)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">9.72%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Technician (n = 48)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">16.67%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Seniority (Years)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&lt;=5 (n = 137)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">47.57%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&gt;5 - 10 (n = 132)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">45.83%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">&gt;10 (n = 19)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">6.60%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Quarter night </p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Yes (n = 205)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">71.18%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">No (n = 83)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">28.82%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Exposure to loud noise</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">Yes (n = 36)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">12.5%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="48.91%"><p style="text-align:left">No (n = 252)</p></td> 
       <td class="aleft" width="51.09%"><p style="text-align:left">87.5%</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>IIQ: Interquartile II.</p>
   </sec>
   <sec id="s3_2">
    <title>3.2. Clinical and Biological Characteristics of the Participants</title>
    <p>The majority of respondents (85.42%) had no history of cardiovascular disease, and around one-eighth (12.16%) had a history of hypertension. Over half of the respondents were overweight or obese (60.42%) and drank alcohol (54.17%). Hypertension was prevalent in 44.79% of respondents, 42% of whom had renal abnormalities. Five of these individuals received an emergency nephrological consultation (<xref ref-type="table" rid="table2">
      Table 2
     </xref>).</p>
    <table-wrap id="table2">
     <label>
      <xref ref-type="table" rid="table2">
       Table 2
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.142761-"></xref>Table 2. Clinical and biological of the subjects surveyed.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">Variables</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">n = 288</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Medical history</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Diabetes (n = 7)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">2.42%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">AH (n = 35)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">12.16%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">None (n = 246)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">85.42%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Alcohol</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 156)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">54.17%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">No (n = 132)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">45.83%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Tabacco</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 45)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">15.62%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">No (n = 243)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">84.38%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">BMI</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">BMI median (IIQ)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">26 (15 - 54)</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Under-nutrition (n = 3)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">1.04%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Normal (n = 111)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">38.54%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Overweight (n = 111)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">38.54%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">Obesity (n = 63)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">21.88%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Pratising sport</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 16)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">5.56%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">No (n = 272)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">94.44%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td aleft" width="56.87%"><p style="text-align:left">Median heart rate (IIQ)</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="43.13%"><p style="text-align:left">78 (40 - 112)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">AH</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 129)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">44.79%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">No (n = 159)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">55.21%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Kidney damage</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 121)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">42%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="56.87%"><p style="text-align:left">No (n = 167)</p></td> 
       <td class="custom-bottom-td aleft" width="43.13%"><p style="text-align:left">58%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td aleft" width="56.87%"><p style="text-align:left">DBP median (IIQ)</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="43.13%"><p style="text-align:left">86 (52 - 118)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td aleft" width="56.87%"><p style="text-align:left">SBP median (IIQ)</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="43.13%"><p style="text-align:left">134 (94 - 191)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="56.87%"><p style="text-align:left">Hyperglycaemia</p></td> 
       <td class="custom-top-td aleft" width="43.13%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">Yes (n = 15)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">5.21%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="56.87%"><p style="text-align:left">No (n = 273)</p></td> 
       <td class="aleft" width="43.13%"><p style="text-align:left">94.79%</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>DBP: Diastolic blood pressure; SBP: Systolic blood pressure; BMI: Body Mass Index; AH: Arterial Hypertension.</p>
   </sec>
   <sec id="s3_3">
    <title>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>3.3. Associated Factors</title>
    <p>According to the results of the univariate analysis, the occurrence of arterial hypertension was associated with age (OR 0.32 [0.13 - 0.77], p = 0.00), occupational category (OR 0.37 [0.15 - 0.91], p = 0.02), seniority (OR 0.46 [0.28 - 0.74], p = 0.00), history of diabetes (OR 7.71 [0.91 - 64.86], p = 0.03) and alcohol consumption (OR 2.25 [1.39 - 3.63], p = 0.00) (<xref ref-type="table" rid="table3">
      Table 3
     </xref> and <xref ref-type="table" rid="table4">
      Table 4
     </xref>).</p>
    <p>Multivariate analysis identified two factors associated with incident arterial hypertension: a history of diabetes (OR = 36.42 [4.07 - 325.89], p = 0.00) and alcohol consumption (OR = 1.99 [1.21 - 3.31], p = 0.007) (<xref ref-type="table" rid="table5">
      Table 5
     </xref>).</p>
    <table-wrap id="table3">
     <label>
      <xref ref-type="table" rid="table3">
       Table 3
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.142761-"></xref>Table 3. Univariate analysis, association between risk factors and the AH.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td rowspan="2" class="aleft" width="23.53%"><p style="text-align:left"></p></td> 
       <td rowspan="2" class="acenter" width="13.24%"><p style="text-align:center">AH (+)</p></td> 
       <td rowspan="2" class="acenter" width="14.71%"><p style="text-align:center">AH (−)</p></td> 
       <td rowspan="2" class="acenter" width="11.76%"><p style="text-align:center">P value</p></td> 
       <td class="acenter" width="36.76%" colspan="3"><p style="text-align:center">Univariate analysis</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="13.23%"><p style="text-align:center">Odds ratio</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="23.53%" colspan="2"><p style="text-align:center">Trusted interval at 95%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Age (Years)</p></td> 
       <td class="custom-top-td aleft" width="13.24%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="14.71%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="13.23%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">&lt;=30 (n = 31)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">7 (22.58%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">24 (77.42%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.32</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.13</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.77</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">&gt;30 - 50 (n = 236)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">107 (45.34%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">129 (54.66%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.40</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">1.13</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.61</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">2.07</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">&gt;50 (n = 21)</p></td> 
       <td class="custom-bottom-td acenter" width="13.24%"><p style="text-align:center">15 (71.43%)</p></td> 
       <td class="custom-bottom-td acenter" width="14.71%"><p style="text-align:center">6 (28.57%)</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="13.23%"><p style="text-align:center">3.35</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">1.26</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">8.91</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Sex</p></td> 
       <td class="custom-top-td acenter" width="13.24%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="14.71%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="13.23%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Woman (n = 39)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">16 (41.03%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">23 (58.97%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.37</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.83</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.42</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">1.66</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">Man (n = 249)</p></td> 
       <td class="custom-bottom-td acenter" width="13.24%"><p style="text-align:center">113 (45.38%)</p></td> 
       <td class="custom-bottom-td acenter" width="14.71%"><p style="text-align:center">136 (54.62%)</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.37</p></td> 
       <td class="custom-bottom-td acenter" width="13.23%"><p style="text-align:center">1.19</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.60</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">2.36</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Job category</p></td> 
       <td class="custom-top-td acenter" width="13.24%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="14.71%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="13.23%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Supervisor (n = 39)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">22 (56.41%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">17 (43.59%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.08</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">1.71</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.86</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">3.39</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Management (n = 4)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">3 (75%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">1 (25%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.23</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">3.76</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.38</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">36.60</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Worker (n = 142)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">70 (49.3%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">72 (50.7%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.08</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">1.43</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.89</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">2.28</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Intern (n = 28)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">7 (25%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">21 (75%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.02</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.37</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.15</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.91</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">Technician (n = 48)</p></td> 
       <td class="custom-bottom-td acenter" width="13.24%"><p style="text-align:center">16 (33.33%)</p></td> 
       <td class="custom-bottom-td acenter" width="14.71%"><p style="text-align:center">32 (66.67%)</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.05</p></td> 
       <td class="custom-bottom-td acenter" width="13.23%"><p style="text-align:center">0.56</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.29</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">1.07</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Seniority</p></td> 
       <td class="custom-top-td aleft" width="13.24%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="14.71%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="13.23%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.76%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">&lt;=5 (n = 137)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">48 (35.04%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">89 (64.96%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.46</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.28</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.74</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">&gt;5 - 10 (n = 132)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">70 (53.03%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">62 (46.97%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">1.85</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">1.15</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">2.97</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">&gt;10 (n = 19)</p></td> 
       <td class="custom-bottom-td acenter" width="13.24%"><p style="text-align:center">11 (57.89%)</p></td> 
       <td class="custom-bottom-td acenter" width="14.71%"><p style="text-align:center">8 (42.11%)</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.17</p></td> 
       <td class="custom-bottom-td acenter" width="13.23%"><p style="text-align:center">1.75</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.68</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">4.51</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Exposure to loud noise</p></td> 
       <td class="custom-top-td acenter" width="13.24%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="14.71%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="13.23%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Yes (n = 36)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">15 (41.67%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">21 (58.33%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.41</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.86</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.42</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">1.75</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">No (n = 252)</p></td> 
       <td class="custom-bottom-td acenter" width="13.24%"><p style="text-align:center">114 (45.24%)</p></td> 
       <td class="custom-bottom-td acenter" width="14.71%"><p style="text-align:center">138 (54.76%)</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.41</p></td> 
       <td class="custom-bottom-td acenter" width="13.23%"><p style="text-align:center">1.15</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">0.57</p></td> 
       <td class="custom-bottom-td acenter" width="11.76%"><p style="text-align:center">2.34</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">Quarter night</p></td> 
       <td class="custom-top-td acenter" width="13.24%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="14.71%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="13.23%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.76%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">Yes (n = 205)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">89 (43.41%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">116 (56.59%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.27</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">0.82</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.49</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">1.37</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="23.53%"><p style="text-align:left">No (n = 83)</p></td> 
       <td class="acenter" width="13.24%"><p style="text-align:center">40 (48.19%)</p></td> 
       <td class="acenter" width="14.71%"><p style="text-align:center">43 (51.81%)</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.27</p></td> 
       <td class="acenter" width="13.23%"><p style="text-align:center">1.21</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">0.72</p></td> 
       <td class="acenter" width="11.76%"><p style="text-align:center">2.02</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>AH: Arterial Hypertension.</p>
    <table-wrap id="table4">
     <label>
      <xref ref-type="table" rid="table4">
       Table 4
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.142761-"></xref>Table 4. Univariate analysis, association between risk factors and the AH.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td rowspan="2" class="aleft" width="22.07%"><p style="text-align:left"></p></td> 
       <td rowspan="2" class="acenter" width="15.44%"><p style="text-align:center">AH (+)</p></td> 
       <td rowspan="2" class="acenter" width="15.44%"><p style="text-align:center">AH (−)</p></td> 
       <td rowspan="2" class="acenter" width="10.30%"><p style="text-align:center">P-value</p></td> 
       <td class="custom-bottom-td acenter" width="36.76%" colspan="3"><p style="text-align:center">Univariate analysis</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="12.95%"><p style="text-align:center">Odds ratio</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="23.81%" colspan="2"><p style="text-align:center">Truste interval at 95%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Medical history</p></td> 
       <td class="custom-top-td aleft" width="15.44%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="15.44%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="10.30%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="12.95%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="11.38%"><p style="text-align:left"></p></td> 
       <td class="custom-top-td aleft" width="12.43%"><p style="text-align:left"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Diabetes (n = 7)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">6 (14.29%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">1 (85.71%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.03</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">7.71</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.91</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">64.86</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="22.07%"><p style="text-align:left">None (n = 246)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">88 (35.77%)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">158 (64.23%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="12.95%"><p style="text-align:center">0.01</p></td> 
       <td class="custom-bottom-td acenter" width="11.38%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="12.43%"><p style="text-align:center">0.10</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Alcohol</p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.95%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.38%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.43%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Yes (n = 156)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">84 (53.85%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">72 (46.15%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">2.25</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">1.39</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">3.63</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="22.07%"><p style="text-align:left">No (n = 132)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">45 (34.09%)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">87 (65.91%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="12.95%"><p style="text-align:center">0.44</p></td> 
       <td class="custom-bottom-td acenter" width="11.38%"><p style="text-align:center">0.27</p></td> 
       <td class="custom-bottom-td acenter" width="12.43%"><p style="text-align:center">0.71</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Tabacco</p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.95%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.38%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.43%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Yes (n = 45)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">24 (53.33%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">21 (46.67%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.13</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">1.50</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.79</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">2.84</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="22.07%"><p style="text-align:left">No (n = 243)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">105 (43.21%)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">138 (56.79%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">0.13</p></td> 
       <td class="custom-bottom-td acenter" width="12.95%"><p style="text-align:center">0.66</p></td> 
       <td class="custom-bottom-td acenter" width="11.38%"><p style="text-align:center">0.35</p></td> 
       <td class="custom-bottom-td acenter" width="12.43%"><p style="text-align:center">1.20</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Pratising sport</p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.95%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.38%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.43%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Yes (n = 16)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">10 (62.5%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">6 (37.5%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.11</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">2.14</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.75</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">6.06</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="22.07%"><p style="text-align:left">No (n = 272)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">119 (43.75%)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">153 (56.25%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">0.11</p></td> 
       <td class="custom-bottom-td acenter" width="12.95%"><p style="text-align:center">0.46</p></td> 
       <td class="custom-bottom-td acenter" width="11.38%"><p style="text-align:center">0.16</p></td> 
       <td class="custom-bottom-td acenter" width="12.43%"><p style="text-align:center">1.32</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Kidney damage</p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.95%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.38%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.43%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Yes (n = 121)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">56 (46.28%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">65 (53.72%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.37</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">1.10</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.69</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">1.77</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="22.07%"><p style="text-align:left">No (n = 167)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">73 (43.71%)</p></td> 
       <td class="custom-bottom-td acenter" width="15.44%"><p style="text-align:center">94 (56.29%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">0.37</p></td> 
       <td class="custom-bottom-td acenter" width="12.95%"><p style="text-align:center">0.90</p></td> 
       <td class="custom-bottom-td acenter" width="11.38%"><p style="text-align:center">0.56</p></td> 
       <td class="custom-bottom-td acenter" width="12.43%"><p style="text-align:center">1.44</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="22.07%"><p style="text-align:left">Biochemistry</p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="15.44%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.95%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="11.38%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="12.43%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">High urea (n = 6)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">4 (66.67%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">2 (33.33%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.24</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">2.51</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.45</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">13.93</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">High creatinine (n = 63)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">32 (50.79%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">31 (49.21%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.17</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">1.36</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.77</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">2.38</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="22.07%"><p style="text-align:left">Hyperglycemia (n = 15)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">10 (66.67%)</p></td> 
       <td class="acenter" width="15.44%"><p style="text-align:center">5 (33.33%)</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.06</p></td> 
       <td class="acenter" width="12.95%"><p style="text-align:center">2.58</p></td> 
       <td class="acenter" width="11.38%"><p style="text-align:center">0.86</p></td> 
       <td class="acenter" width="12.43%"><p style="text-align:center">7.77</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>AH: Arterial Hypertension.</p>
    <table-wrap id="table5">
     <label>
      <xref ref-type="table" rid="table5">
       Table 5
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.142761-"></xref>Table 5. Multivariate analysis, association between risk factors and the AH.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left"></p></td> 
       <td class="aleft" width="20.58%" colspan="2"><p style="text-align:left"></p></td> 
       <td class="custom-bottom-td acenter" width="32.36%" colspan="4"><p style="text-align:center">Univariate analysis</p></td> 
       <td class="custom-bottom-td acenter" width="30.87%" colspan="4"><p style="text-align:center">Multivariate analysis</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left"></p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">AH (+)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">AH (−)</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="7.36%"><p style="text-align:center">P-value</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="10.29%"><p style="text-align:center">Odds ratio</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="14.71%" colspan="2"><p style="text-align:center">Truste interval at 95%</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="7.35%"><p style="text-align:center">P-value</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="10.30%"><p style="text-align:center">Odds ratio</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="13.23%" colspan="2"><p style="text-align:center">Truste interval at 95%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Age</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">&lt;=30 </p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">7 (22.58%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">24 (77.42%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.001</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">0.32</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.13</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.77</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.58</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.97</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.373</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">2.55</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">&gt;30 - 50 </p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">107 (45.34%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">129 (54.66%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.4</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.13</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.61</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">2.07</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">&gt;50 </p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">15 (71.43%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">6 (28.57%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.001</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">3.35</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">1.26</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">8.91</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">0.59</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">1.02</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">0.36</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">2.89</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Job category</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Supervisor</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">22 (56.41%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">17 (43.59%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.08</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.71</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.86</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">3.39</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Management</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">3 (75%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1 (25%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.23</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">3.76</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.38</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">36.6</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Worker</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">70 (49.3%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">72 (50.7%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.08</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.43</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.89</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">2.28</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Intern</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">7 (25%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">21 (75%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.02</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">0.37</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.15</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.91</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.58</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">1</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.37</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">2.63</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">Technician</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">16 (33.33%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">32 (66.67%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.05</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">0.56</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.29</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">1.07</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Seniority</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">&lt;=5 </p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">48 (35.04%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">89 (64.96%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.001</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">0.46</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.28</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.74</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.55</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">1</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.58</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">1.71</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">&gt;5 - 10</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">70 (53.03%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">62 (46.97%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.001</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.85</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">1.15</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">2.97</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.43</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.92</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.55</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">1.55</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">&gt;10 </p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">11 (57.89%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">8 (42.11%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.17</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">1.75</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.68</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">4.51</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">-</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">-</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Medical history</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Diabetes</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">6 (14.29%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1 (85.71%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.03</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">7.71</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.91</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">64.86</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">36.42</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">4.07</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">325.89</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">None</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">88 (35.77%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">158 (64.23%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">0.01</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.1</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">0.52</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">1.02</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">0.62</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">1.65</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Alcohol</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Yes</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">84 (53.85%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">72 (46.15%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.00</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">2.25</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">1.39</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">3.63</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.007</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">1.99</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">1.21</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">3.31</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">No</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">45 (34.09%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">87 (65.91%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.00</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">0.44</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.27</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.71</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">0.000</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">2.55</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">1.72</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">3.80</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Tabacco</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Yes (n = 45)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">24 (53.33%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">21 (46.67%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.13</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.50</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.79</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">2.84</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.21</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">2.24</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">1.43</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">4.52</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">No (n = 243)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">105 (43.21%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">138 (56.79%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.13</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">0.66</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.35</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">1.20</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">0.20</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">1.12</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">0.61</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">2.27</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Pratising sport</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Yes (n = 16)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">10 (62.5%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">6 (37.5%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.11</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">2.14</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.75</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">6.06</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.19</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">3.41</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.87</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">7.83</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="16.18%"><p style="text-align:left">No (n = 272)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">119 (43.75%)</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">153 (56.25%)</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.11</p></td> 
       <td class="custom-bottom-td acenter" width="10.29%"><p style="text-align:center">0.46</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">0.16</p></td> 
       <td class="custom-bottom-td acenter" width="7.36%"><p style="text-align:center">1.32</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">0.18</p></td> 
       <td class="custom-bottom-td acenter" width="10.30%"><p style="text-align:center">3.55</p></td> 
       <td class="custom-bottom-td acenter" width="5.88%"><p style="text-align:center">2.53</p></td> 
       <td class="custom-bottom-td acenter" width="7.35%"><p style="text-align:center">4.99</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="16.18%"><p style="text-align:left">Biochemistry</p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.29%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.36%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="10.30%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="5.88%"><p style="text-align:center"></p></td> 
       <td class="custom-top-td acenter" width="7.35%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">High urea (n = 6)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">4 (66.67%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">2 (33.33%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.24</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">2.51</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.45</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">13.93</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">1.20</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.58</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.074</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">1.12</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">High creatinine (n = 63)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">32 (50.79%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">31 (49.21%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.17</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">1.36</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.77</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">2.38</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.131</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">1.61</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">1.03</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">2.52</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="16.18%"><p style="text-align:left">Hyperglycemia </p><p style="text-align:left">(n = 15)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">10 (66.67%)</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">5 (33.33%)</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.06</p></td> 
       <td class="acenter" width="10.29%"><p style="text-align:center">2.58</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">0.86</p></td> 
       <td class="acenter" width="7.36%"><p style="text-align:center">7.77</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.22</p></td> 
       <td class="acenter" width="10.30%"><p style="text-align:center">0.075</p></td> 
       <td class="acenter" width="5.88%"><p style="text-align:center">0.031</p></td> 
       <td class="acenter" width="7.35%"><p style="text-align:center">0.18</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>AH: Arterial Hypertension.</p>
   </sec>
  </sec><sec id="s4">
   <title>4. Discussion</title>
   <p>The aim of our study was to determine the prevalence of hypertension and its associated factors among mining workers. We found that the prevalence of high blood pressure was 44.79%. We found that hypertension was associated with a history of diabetes and alcohol consumption.</p>
   <sec id="s4_1">
    <title>
     <xref ref-type="bibr" rid="scirp.142761-"></xref>4.1. Limits of the Study</title>
    <p>The study may be weakened by selection and confounding biases related to the type of study and the possibility of essential hypertension. However, the methodology we employed mitigated the impact of these biases. Logistic regression was used to address confounding bias. Selection bias was mitigated by calculating the minimum sample size and accounting for a 10% non-response rate. Nevertheless, our results must be interpreted with great caution, given that the study did not include all workers in the country’s mining sector.</p>
   </sec>
   <sec id="s4_2">
    <title>4.2. Socio-Professional Characteristics of the Participants</title>
    <p>In our study, we found a strong male predominance of 86.46%. This may be related to the nature of the work in the African context in which our study was conducted. In the mining sector, for example, women are more likely to occupy administrative roles, which are generally considered to be less demanding. Several studies in this country and elsewhere support our findings <xref ref-type="bibr" rid="scirp.142761-3">
      [3]
     </xref> <xref ref-type="bibr" rid="scirp.142761-21">
      [21]
     </xref> <xref ref-type="bibr" rid="scirp.142761-22">
      [22]
     </xref> <xref ref-type="bibr" rid="scirp.142761-24">
      [24]
     </xref>. We also found that the vast majority of participants (71.18%) worked night shifts. This finding may also explain why there are few women working in this company, particularly in an African context where women are generally responsible for raising children at home.</p>
   </sec>
   <sec id="s4_3">
    <title>4.3. Clinical and Biological Characteristics of the Participants</title>
    <p>The study showed a high prevalence of hypertension (44.79%). Our results were similar to those found in hospitals in Gabon (45.2%), among noise-exposed workers in Taiwan region (43.5%), and in Saudi Arabia, Ethiopia and Thailand (44% and 45%, respectively) <xref ref-type="bibr" rid="scirp.142761-10">
      [10]
     </xref> <xref ref-type="bibr" rid="scirp.142761-20">
      [20]
     </xref> <xref ref-type="bibr" rid="scirp.142761-25">
      [25]
     </xref>-<xref ref-type="bibr" rid="scirp.142761-27">
      [27]
     </xref>. However, they were lower than the prevalence reported in several studies in the occupational literature <xref ref-type="bibr" rid="scirp.142761-12">
      [12]
     </xref> <xref ref-type="bibr" rid="scirp.142761-28">
      [28]
     </xref>. However, our results were higher than those reported in several studies in occupational settings in Gabon (13.48%, 35.2%, 37%, 39.9%), the Democratic Republic of Congo (32.5%) and Senegal (17%) <xref ref-type="bibr" rid="scirp.142761-3">
      [3]
     </xref> <xref ref-type="bibr" rid="scirp.142761-6">
      [6]
     </xref> <xref ref-type="bibr" rid="scirp.142761-11">
      [11]
     </xref> <xref ref-type="bibr" rid="scirp.142761-19">
      [19]
     </xref> <xref ref-type="bibr" rid="scirp.142761-21">
      [21]
     </xref> <xref ref-type="bibr" rid="scirp.142761-22">
      [22]
     </xref>. These differences in the prevalence of hypertension within and between countries could be explained by variations in occupational activities and working conditions within each company <xref ref-type="bibr" rid="scirp.142761-12">
      [12]
     </xref> <xref ref-type="bibr" rid="scirp.142761-25">
      [25]
     </xref>. Additionally, changing lifestyles and the increasing prevalence of non-communicable diseases, such as cardiovascular disease, could also explain these differences <xref ref-type="bibr" rid="scirp.142761-29">
      [29]
     </xref>.</p>
   </sec>
   <sec id="s4_4">
    <title>4.4. Associated Factors</title>
    <p>Univariate/multivariate analysis</p>
    <p>In our study, we found that factors such as age, history of diabetes, alcohol consumption, occupational category, and duration of work were associated with the development of hypertension. Our results confirm those reported in the literature regarding the association of these factors with hypertension development <xref ref-type="bibr" rid="scirp.142761-3">
      [3]
     </xref> <xref ref-type="bibr" rid="scirp.142761-6">
      [6]
     </xref> <xref ref-type="bibr" rid="scirp.142761-24">
      [24]
     </xref> <xref ref-type="bibr" rid="scirp.142761-30">
      [30]
     </xref> <xref ref-type="bibr" rid="scirp.142761-31">
      [31]
     </xref>. However, factors such as night shift work and noise exposure were not associated with the development of hypertension in our study. Our results differ from those reported in the literature on this subject <xref ref-type="bibr" rid="scirp.142761-25">
      [25]
     </xref> <xref ref-type="bibr" rid="scirp.142761-32">
      [32]
     </xref>. Additionally, obesity was not associated with the development of hypertension in our study. Our results also differed from those reported in the literature on this subject <xref ref-type="bibr" rid="scirp.142761-3">
      [3]
     </xref> <xref ref-type="bibr" rid="scirp.142761-10">
      [10]
     </xref> <xref ref-type="bibr" rid="scirp.142761-33">
      [33]
     </xref>. This difference may be related to the small sample size of our study. The history of diabetes and alcohol consumption were the only two factors that predicted the development of hypertension in our study. High blood pressure results from too much pressure in the arteries. This can be caused by endothelial dysfunction, vascular inflammation, arterial remodelling, atherosclerosis, and many other factors associated with diabetes onset. This justifies the strong link between diabetes and hypertension <xref ref-type="bibr" rid="scirp.142761-34">
      [34]
     </xref>. Our results are consistent with those reported in the literature <xref ref-type="bibr" rid="scirp.142761-3">
      [3]
     </xref> <xref ref-type="bibr" rid="scirp.142761-30">
      [30]
     </xref> <xref ref-type="bibr" rid="scirp.142761-31">
      [31]
     </xref> <xref ref-type="bibr" rid="scirp.142761-35">
      [35]
     </xref>. Furthermore, a study conducted by Makosso et al. in 2025 at a mining company in Moanda, Gabon, also found that alcohol consumption was a factor associated with the onset of hypertension. Our results were consistent with those reported in this study <xref ref-type="bibr" rid="scirp.142761-6">
      [6]
     </xref>.</p>
   </sec>
  </sec><sec id="s5">
   <title>5. Conclusion</title>
   <p>The study reveals a high prevalence of hypertension, as well as the associated factors of diabetes and alcohol consumption. Setting up an occupational health service would enable close medical monitoring of workers with chronic diseases. This will allow treatment compliance to be monitored, discussions to be held with the attending physician particularly in the case of diabetes and patient appointments to be organised. Depending on the progress of the disease and the worker’s job, adjustments or changes to the role can also be proposed. In the case of alcohol addiction among certain workers, this service can offer therapy sessions with specialists. Potential health promotion programs will be based on screening and raising awareness of diabetes and alcohol among workers. In-company counselling units with specialists will be set up, particularly for alcohol addiction. Collective sports activities will be encouraged within and outside the company. Factors such as the distance travelled by workers and the reconciliation of social and professional life should also be considered when developing hypertension. Workplace factors such as noise pollution, shift work, night work, and unfavourable psychosocial aspects of the working environment may be associated with the onset of hypertension. The occupational health service will help implement effective collective and individual measures to safeguard workers’ health. Multicentre cohort studies should be carried out in the Gabonese workplace to determine the national prevalence of hypertension, and to develop screening strategies and collective and specific prevention measures for this disease in each sector.</p>
  </sec><sec id="s6">
   <title>Acknowledgements</title>
   <p>The authors would like to thank the authorities at the Franceville Polyclinic for allowing the study to be conducted. They would also like to thank the patients who agreed to participate.</p>
  </sec><sec id="s7">
   <title>Authors’ Contributions</title>
   <p>All authors participated in the preparation of the manuscript. They have read and approved the final version.</p>
  </sec>
 </body><back>
  <ref-list>
   <title>References</title>
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