<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">JAMP</journal-id><journal-title-group><journal-title>Journal of Applied Mathematics and Physics</journal-title></journal-title-group><issn pub-type="epub">2327-4352</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/jamp.2021.910165</article-id><article-id pub-id-type="publisher-id">JAMP-112815</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Physics&amp;Mathematics</subject></subj-group></article-categories><title-group><article-title>
 
 
  Beyond a Quartic Polynomial Modeling of the DNA Double-Helix Genetic Code
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Hans</surname><given-names>Hermann Otto</given-names></name><xref ref-type="aff" rid="aff1"><sub>1</sub></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Materials Science and Crystallography, Clausthal University of Technology, Clausthal-Zellerfeld, Germany</addr-line></aff><pub-date pub-type="epub"><day>29</day><month>09</month><year>2021</year></pub-date><volume>09</volume><issue>10</issue><fpage>2558</fpage><lpage>2577</lpage><history><date date-type="received"><day>14,</day>	<month>September</month>	<year>2021</year></date><date date-type="rev-recd"><day>26,</day>	<month>October</month>	<year>2021</year>	</date><date date-type="accepted"><day>29,</day>	<month>October</month>	<year>2021</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p><html>
 <head></head>
 
  By combination of finite number theory and quantum information, the complete quantum information in the 
  <em>DNA</em> genetic code has been made likely by 
  <em>Planat et al</em>. (2020). In the present contribution a varied quartic polynomial contrasting the polynomial used by 
  <em>Planat et al</em>. is proposed that considered apart from the golden mean also the fifth power of this dominant number of nature to adapt the code information. The suggested polynomial is denoted as 
  <em>g</em>(
  <em>x</em>) = 
  <em>x</em>
  <sup>4</sup> - 
  <em>x</em>
  <sup>3</sup> - (4 - 
  <em>&amp;#981;</em>
  <sup>2</sup> )
  <em>x</em>
  <sup>2</sup> + (4 – 
  &amp;#981;
  <sup>2</sup>)x + 1, where 
  <img src="Edit_40efe764-d690-499f-8424-129f9ca46f78.bmp" alt="" /> is the golden mean. Its roots are changed to more golden mean based ones in comparison to the 
  <em>Planat</em> polynomial. The new coefficients 4 – 
  <em>&amp;#981;</em>
  <sup>2</sup> instead of 4 would implement the fifth power of the golden mean indirectly applying 
  <img src="Edit_5b44b644-3f59-4fad-a586-ec5345ba6be4.bmp" alt="" />. As an outlook, it should be emphesized that the connection between genetic code and resonance code of the 
  <em>DNA</em> may lead us to a full understanding of how nature stores and processes compacted information and what indeed is consciousness linking everything with each other suggestedly mediated by all-pervasive dark constituents of matter respectively energy. The number-theoretical approach to 
  <em>DNA</em> coding leads to the question about the helical structure of the electron.
 
</html></p></abstract><kwd-group><kwd>&lt;i&gt;DNA&lt;/i&gt; Genetic Code</kwd><kwd> &lt;i&gt;DNA&lt;/i&gt; Resonance Code</kwd><kwd> Qartic Polymial</kwd><kwd> Golden Mean</kwd><kwd> Silver Mean</kwd><kwd> Fifth Power of the Golden Mean</kwd><kwd> Fiboacci Number 13</kwd><kwd> &lt;i&gt;α&lt;/i&gt;-Helix</kwd><kwd> Icosahedron Equation</kwd><kwd> Number Theory</kwd><kwd> Quantum Computation</kwd><kwd> Consciousness</kwd><kwd> Dark Energy</kwd><kwd> Electron’s Structure</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>In a more literary parlance, the genetic code of DNA is the very language of life, made up of four nucleotides (A = adenine, C = cytosine, G = guanine, T = thymine) combined to 64 three-letter words, the codons. The code can be read by cellular complexes, the ribosomes, and the information translated to produce proteins. In a brilliant contribution Planatet al. set out unrevealing the complete quantum information in the DNA genetic code by combining finite number theory and quantum information [<xref ref-type="bibr" rid="scirp.112815-ref1">1</xref>]. The cited authors have used a quartic polynomial containing the golden mean φ in its structure (see Appendix). Intuitively, the present author suspects that in addition to the golden mean, also the fifth power of this number should play an important role in mapping the genetic code owed to the fact that this number is observed extremely frequently in nature, covering examples from microscopic to cosmic scale [<xref ref-type="bibr" rid="scirp.112815-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref4">4</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref5">5</xref>]. So, one may argue that this feature should also be found in some way in the genetic code. A little varied quartic polynomial can deliver such an implementation of φ<sup>5</sup> by replacing the starting polynomial coefficients adequately. This was described in Chapter 2. In times of a viral pandemic, it is essential to know the genetic code of DNA respectively surface proteins in order to effectively block the replication capacity of any pathogenic virus via this route. A further practical aspect of research in this direction is to pave the way for quantum computation under ambient conditions. Recently, a very creative review for understanding of what may be important when dealing with such suggestions has been given by Savelyevet al. connecting the DNA resonance code to the neural code [<xref ref-type="bibr" rid="scirp.112815-ref6">6</xref>]. When translating such connections in the parlance of phase transition, again one comes back to the golden ratio respectively its fifth power [<xref ref-type="bibr" rid="scirp.112815-ref4">4</xref>], both considered as fundamental numbers of nature.</p><p>The presented contribution is a short excerpt from a more comprehensive review coming soon about new aspects of helical structures in general [<xref ref-type="bibr" rid="scirp.112815-ref7">7</xref>]. Therein a didactic explanation for the characteristic diffraction pattern of a helix (double-helix) will be presented in detail.</p><p>Finally, the algebraic-geometrical approach to the code of the DNA and secondary protein structures leads to the question what structure a fundamental particle like the electron has.</p><p>In the Appendix some supplements were made comparing the just mentioned quartic polynomials with double well potential curves respectively the Hardy probability function [<xref ref-type="bibr" rid="scirp.112815-ref2">2</xref>].</p></sec><sec id="s2"><title>2. Varying the Quartic Polynomial f(x)</title><p>For a better understanding of the solution of polynomial equations, the recent work of Tehrani [<xref ref-type="bibr" rid="scirp.112815-ref8">8</xref>] is highly recommended.</p><p>The starting Planat quartic polynomial (PQP) given in [<xref ref-type="bibr" rid="scirp.112815-ref1">1</xref>] is</p><p>f ( x ) = x 4 − x 3 − 4 x 2 + 4 x + 1 (1)</p><p>Its curve is illustrated in <xref ref-type="fig" rid="fig1">Figure 1</xref> and its four roots (zeros) are presented in <xref ref-type="table" rid="table1">Table 1</xref> according to [<xref ref-type="bibr" rid="scirp.112815-ref1">1</xref>]. What happens, if the polynomial would be slightly varied by replacing the coefficients 4 by 4 − φ 2 = 3 + φ , where φ is the golden</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> Roots of the quartic polynomials f ( x ) and g ( x ) </title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Roots</th><th align="center" valign="middle"  colspan="2"  >f ( x )</th><th align="center" valign="middle"  colspan="2"  >g ( x )</th></tr></thead><tr><td align="center" valign="middle" >r<sub>1 </sub></td><td align="center" valign="middle" >− 2 cos ( π 15 )</td><td align="center" valign="middle" >−1.956295…</td><td align="center" valign="middle" >≈ − ( φ − 1 + φ 3 )</td><td align="center" valign="middle" >−1.8516618…</td></tr><tr><td align="center" valign="middle" >r<sub>3 </sub></td><td align="center" valign="middle" >− 2 cos ( 7 π 15 )</td><td align="center" valign="middle" >−0.209056…</td><td align="center" valign="middle" >≈ − φ 3 = − 0.2360679 ⋯</td><td align="center" valign="middle" >−0.2283086…</td></tr><tr><td align="center" valign="middle" >r<sub>2 </sub></td><td align="center" valign="middle" >− 2 cos ( 11 π 15 )</td><td align="center" valign="middle" >1.338261…</td><td align="center" valign="middle"  rowspan="2"  >− 2 cos ( 12 π 15 ) = φ − 1</td><td align="center" valign="middle"  rowspan="2"  >1.61803398…</td></tr><tr><td align="center" valign="middle" >r<sub>4 </sub></td><td align="center" valign="middle" >− 2 cos ( 13 π 15 )</td><td align="center" valign="middle" >1.827091…</td></tr></tbody></table></table-wrap><p>mean: φ = 5 − 1 2 ?</p><p>The coefficients now used possibly represent limits and can be recast by</p><p>4 − φ 2 = 13 + φ 5 = 3.6180339887 ⋯ (2)</p><p>In this way one would implement the fifth power of the golden mean indirectly. The new polynomial is denoted as g ( x ) and is given by</p><p>g ( x ) = x 4 − x 3 − ( 4 − φ 2 ) x 2 + ( 4 − φ 2 ) x + 1 (3)</p><p>Its roots are changed to more golden mean based ones in comparison to the starting polynomial (see <xref ref-type="table" rid="table1">Table 1</xref>). Both quartic polynomials can be compared in <xref ref-type="fig" rid="fig1">Figure 1</xref>. The curve for g ( x ) is somewhat flattened and compressed in comparison to the starting curve.</p><p>Remarkably, for g ( x ) two zeros r<sub>2</sub> and r<sub>4</sub> meet at x = φ − 1 . This flatten out of the curve around zero may be important, when considering the polynomial as a template for a potential energy model of the DNA double helix and critical behavior. About double well potential important in quantum information theory see Appendix. The maximum of g ( x ) at x = 0.4661 ≈ 2 φ 3 has, similar to the f ( x ) polynomial, a value of</p><p>g max = 1.846288 ⋯ ≈ φ − 1 + φ 3 . (4)</p><p>The effect of the varying coefficients is a pronounced presence of the golden mean hierarchy compared to the starting polynomial. Consequences of the variation of the quartic polynomial with respect to group theoretical changes (entries of the character table) may not be trivial and should be worked out and evaluated by experts. The basic group-theoretical approach [<xref ref-type="bibr" rid="scirp.112815-ref1">1</xref>] was the creation of a group G of order 240 by linking the finite group Z<sub>5</sub> of order 5 with the binary octahedral 2O group of order 48.</p></sec><sec id="s3"><title>3. Helical Structures</title><p>Helical structures dominate or life in the form of the α-helix of proteins [<xref ref-type="bibr" rid="scirp.112815-ref9">9</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref10">10</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref11">11</xref>] or double-helices composed of double-stranded molecule chains of nucleic acids such as DNA [<xref ref-type="bibr" rid="scirp.112815-ref10">10</xref>]. Helical curling of cellulosic micro-fibrils leads to spring-like elastic behavior [<xref ref-type="bibr" rid="scirp.112815-ref12">12</xref>]. Interesting is that helical left-handedness and its opposite can be realized, when a single cellulosic fiber is supported at both ends [<xref ref-type="bibr" rid="scirp.112815-ref13">13</xref>]. Designers have many learnt from the multilayer tube-like structure of wood cell walls leading to superior properties of this natural material [<xref ref-type="bibr" rid="scirp.112815-ref14">14</xref>]. Let’s stick with technical aspects such as making torque from wind. The wake behind multi-bladed rotors can be described by interlaced helical vortices [<xref ref-type="bibr" rid="scirp.112815-ref15">15</xref>]. But also liquid water forms helices of pentagonal or hexagonal symmetry [<xref ref-type="bibr" rid="scirp.112815-ref16">16</xref>]. When subtracting from the regular tetrahedron angle of 109.47˚ the angle arcsin ( φ 5 ) = 5.17 ˚ , where φ is the golden mean, then the bonding angle of H<sub>2</sub>O is quite well adapted giving 104.30˚. This connection to the golden mean hierarchy is intriguing. It is reasonable to assume that water may be involved in two ways in the origin of life, as a liquid medium and as helical scaffold mediating the first assembling of a double-helix of nucleic acids. In contrast, the participation of structurally disordered clay minerals in this process is very unlikely. The fifths power of the golden mean φ<sup>5</sup> in turn is frequently connected to phase transformation from microscopic to cosmic scale [<xref ref-type="bibr" rid="scirp.112815-ref4">4</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref17">17</xref>]. This number may be characterized as a universal one [<xref ref-type="bibr" rid="scirp.112815-ref18">18</xref>]. On the border between hexagonal and pentagonal respectively Fibonacci number governed symmetry our existence is located. Numerical it may be emphasized by the relation φ 5 = 5 φ − 3 .</p><p>Turning to inorganic structures, in 1977 I solved the hexagonal palatinate crystal structure of Cs<sub>2</sub>[Pt(CN)<sub>4</sub>]&#215;H<sub>2</sub>O, in which planar Pt(CN)<sub>4</sub> groups are helical winding down the c axis by means of a 6<sub>1</sub> screw axis (see <xref ref-type="fig" rid="fig2">Figure 2</xref>) [<xref ref-type="bibr" rid="scirp.112815-ref19">19</xref>]. It represents a nice example of helicity in inorganic matter. At that time, I have discussed the Pt orbital overlap of this interesting inorganic compound with Nobel laureate Linus Pauling who solved the structure of the α-helix of proteins 26 years before [<xref ref-type="bibr" rid="scirp.112815-ref9">9</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref10">10</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref11">11</xref>].</p><p>Since that time I was fascinated by the helical structure of matter, but found no time to think about it anymore considering crystal-chemical, biochemical as well as mathematical aspects.</p></sec><sec id="s4"><title>4. A Number-Theoretical Golden Helix Gimmick</title><p>Now we turn to the α-helix peculiarities of proteins where 18 subunits perform 5 turns to reach an identical position when projected down the fiber axis [<xref ref-type="bibr" rid="scirp.112815-ref9">9</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref10">10</xref>]. This means one needs 3.6 subunits per turn. This number is nearby another golden mean derived number (see Equation (2))</p><p>3 + φ = 3.6180339887 ⋯ = 13 + φ 5 = 2 + φ − 5 (5)</p><p>In case of the α-helix, when tentatively using 3.61803… subunits per turn instead of 3.6, one would end with 18 + φ 5 subunits after 5 turns</p><p>5 ( 2 + φ − 1 ) = ( φ 5 + φ − 5 ) φ − 1 = 18 + φ 5 = 18.0901699 ⋯ (6)</p><p>and again the fifth power of the golden mean would be involved.</p><p>What marginal change would such approach of helix breathing produce in the Fourier transform possibly overseen as yet by the interpretation of the diffraction patterns showing quite broad smeared out diffraction spots? An elaborated study of structural variations of B-DNA by interpreting features of its diffraction pattern was recently given in [<xref ref-type="bibr" rid="scirp.112815-ref20">20</xref>].</p><p>The value of 3 + φ = 1 + φ − 2 is also related to an icosahedron as its circumradius when this polyhedron with an edge length of a = 2 is centered at the</p><p>origin [<xref ref-type="bibr" rid="scirp.112815-ref5">5</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref21">21</xref>]. It may be considered as a very important distance frequently found in the following reflections.</p><p>Turning to five-fold symmetrical nucleic acid structures discussed in [<xref ref-type="bibr" rid="scirp.112815-ref1">1</xref>], the regular pentagon with side length a has an area of A<sub>5</sub> calculated by [<xref ref-type="bibr" rid="scirp.112815-ref21">21</xref>]</p><p>A 5 = 5 4 φ 2 3 + φ a 2 = 1.720477403 a 2 (7)</p><p>Another example should be considered with respect to the seven-fold symmetry of complexes like the Lsm1-7 one recently analyzed by Planatet al. [<xref ref-type="bibr" rid="scirp.112815-ref22">22</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref23">23</xref>]. The geometry of a heptagon delivers a connection to the golden mean. The heptagon area A<sub>7</sub> with side length a yields also about 3 + φ in its expression</p><p>A 7 = 7 4 ⋅ tan ( 180 7 ) a 2 = 3.633912 a 2 ≈ ( 3 + φ ) a 2 = 3.618033987 a 2 (8)</p><p>and tan ( 180 7 ) = 0.481574618 ≈ ln ( φ − 1 ) = 0.481211826 (9)</p><p>The relative area difference between heptagon and pentagon can be approximated by</p><p>A 7 − A 5 A 5 = 1.11169295 ≈ 1 + φ 3 = 1.1117859 (10)</p><p>Another example from number theory where the golden mean in form of the square root term 3 + φ is involved but not yet expected is the series of heptagonal numbers generated when heptagons with ascending size are combined [<xref ref-type="bibr" rid="scirp.112815-ref24">24</xref>]. Such figurative heptagonal numbers are generated by the formula [<xref ref-type="bibr" rid="scirp.112815-ref24">24</xref>]</p><p>P n = 5 n 2 − 3 n 2 = 1 , 7 , 18 , 34 , 55 , 81 , ⋯ (11)</p><p>indicating a parity sequence of odd, odd, even, even … and successive Lucas numbers 7 and 18 [<xref ref-type="bibr" rid="scirp.112815-ref25">25</xref>] respectively Fibonacci numbers 34 and 55 [<xref ref-type="bibr" rid="scirp.112815-ref26">26</xref>].</p><p>The sum of reciprocals of this number series shows a result in full glory, if we recast for the first time the already known expression [<xref ref-type="bibr" rid="scirp.112815-ref24">24</xref>] using the golden mean as φ = 5 − 1 2</p><p>∑ n = 1 ∞ 1 P n = 2 3 ( π 2 φ 1 + φ − 2 + ln ( 5 ) + φ − 1 ln ( 1 + φ 2 ) − φ ⋅ ln ( 1 + φ − 2 ) ) = 1.3227792531 ⋯ ≈ 2 3 ln ( 5 ) + 1 4 (12)</p><p>Alternatively, it applies because 1 + φ 2 = φ 1 + φ − 2 = φ 3 + φ</p><p>∑ n = 1 ∞ 1 P n = 2 3 ( π 2 φ 3 + φ + ln ( 5 ) + ln ( φ ) φ + ln ( 3 + φ ) ) = 2 3 ( π 2 φ 3 + φ + ln ( 5 ⋅ φ 1 / φ ) + ln ( 3 + φ ) ) (13)</p><p>where</p><p>ln ( 3 + φ ) ln ( 5 ⋅ φ 1 / φ ) = 2.289438326 ≈ 5 ⋅ φ 1 / φ = 2.29520192 (14)</p><p>and further</p><p>1 2 3 + φ 5 ⋅ φ 1 / φ = 0.414367253 ≈ ( 2 − 1 ) = 0.414213562 (15)</p><p>2 − 1 represents the silver mean here approximated by an expression for the golden mean.</p><p>It indicates that even in the case of seven-fold symmetry a sophisticated numerical relationship to φ, the omnipresent golden code number of life, is given and should be considered in future work on the genetic code and resonance behavior of life. The relation between 3 + φ respectively φ 5 with the circle number π is also remarkable (see also Appendix)</p><p>3 + φ = 1.902113 ≈ 6 π = 1.909859 (16)</p><p>φ 5 = 0.0901699 ≈ 2 − 6 π = 0.0901406 (17)</p></sec><sec id="s5"><title>5. Simple Didactic Approach for the Fourier Transform of a Helix</title><p>The Fourier transform of a helical structure resulting in the integral representation of Bessel functions of different order was first introduced in 1952 by Cochran [<xref ref-type="bibr" rid="scirp.112815-ref9">9</xref>] and can be studied in detail in the monograph “Direct Analysis of Diffraction by Matter” by Hosemann andBagchi [<xref ref-type="bibr" rid="scirp.112815-ref27">27</xref>]. Another recent contribution by Latychevskaia and Fink [<xref ref-type="bibr" rid="scirp.112815-ref28">28</xref>] is recommended as well as that given by Strutz in German [<xref ref-type="bibr" rid="scirp.112815-ref29">29</xref>].</p><p>Our simplified but didactic approach is as follows. If one looks through the projection of a helical structure perpendicular to the filament direction, one will see the mirror image on the back at the helix diameter distance to the front image, somewhat offset in filament direction depending on the helix winding parameters. One can perform the Fourier summation to obtain diffraction intensities exemplified by the projected hexagonal nets of a special Fibonacci micro-tubule with a 13 steps full turn. The starting small cell is helically wound at the twist angle α. It needs 13-times the small cell lattice parameter a<sub>sub</sub> to reach again identity with a large cell lattice point. In this way, the diameter of the smallest geometrically possible microtubule is calculated to be</p><p>d 1 ≈ 13 a s u b ⋅ cos ( α ) / π = 3.5 ⋅ a / π . Interesting is d 6 = 21 ⋅ a π showing a further Fibonnaci number. By a full turn one gains a height in filament direction of</p><p>h 1 = 39 2 a s u b = 3 2 13 ⋅ a s u b = 3.1225 ⋅ a s u b ≈ π ⋅ a s u b . (18)</p><p>More detail of the chosen example can be found in [<xref ref-type="bibr" rid="scirp.112815-ref30">30</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref31">31</xref>]. However, when again choosing in Equation (13) a value of 13 + φ 5 instead of 13 by a small change of the twist, then h 1 a s u b = 3.1333 would better approximate π regardless whether this can be significant in any way.</p><p>The example simplifies helically twisted tubulin microtubules that also show the strongest reinforcement of the ordered pattern when the proto-filament number n equals 13 [<xref ref-type="bibr" rid="scirp.112815-ref32">32</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref33">33</xref>]. Interestingly, according to Penrose andHamedoff tubulin microtubules are considered as the locus where information is stored and assessed, what constitutes our consciousness and cognition [<xref ref-type="bibr" rid="scirp.112815-ref34">34</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref35">35</xref>]. This supports the proposal for a twisted Fibonnaci net as displayed in <xref ref-type="fig" rid="fig3">Figure 3</xref> respectively <xref ref-type="fig" rid="fig4">Figure 4</xref> as a quantum computer bio-template.</p><p>Information may be preserved in tubulin molecules by structural adaption and sequence fluctuations disrupting the helical coherence.</p><p>When removing from the Fibonacci net some atomic stripes one can simulate a double helix. Detailed intensity calculation of such a construct will be given in a forthcoming contribution [<xref ref-type="bibr" rid="scirp.112815-ref7">7</xref>] showing the characteristic X shaped cross of diffraction intensity distribution of a double helix similar to the electron diffraction pattern of B-DNA fibers [<xref ref-type="bibr" rid="scirp.112815-ref36">36</xref>] respectively to the historical X-ray pattern (photo 51) of B-DNA taken by the felt Nobel laureate of hearts Rosalind Franklin [<xref ref-type="bibr" rid="scirp.112815-ref37">37</xref>]. When one works with the projected curved net instead of a flat net, the reflections smear out as result of the introduced coordinate statistics. <xref ref-type="fig" rid="fig3">Figure 3</xref> may</p><p>also help to understand in which way inverted repeat of nucleotides works capable of self-complementary base pairing.</p></sec><sec id="s6"><title>6. Beyond the Icosahedron Equation</title><p>If the genetic information is ultimately coiled and compacted into an icosahedral shape as found in viruses, then another function may come into play, represented by the icosahedron equation mapping for instance the positions of the face centers of an icosahedron with unit in-radius projected onto a complex plane where z is the coordinates [<xref ref-type="bibr" rid="scirp.112815-ref38">38</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref39">39</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref40">40</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref41">41</xref>]</p><p>H ( z , 1 ) = z 20 − 228 z 15 + 494 z 10 + 228 z 5 + 1 (19)</p><p>The roots accordingly correspond to the locations of the face midpoints on the Riemann sphere. Interestingly but not surprisingly, the coefficient ratio yields 494/228 = 13/6 and contains the Fibonacci numerator 13. The coefficients 228 as well as 494 can be replaced by a golden mean based approximation besides number 13</p><p>228 ≈ 4 3 ( 13 + φ 4 3 + φ ) 2 = 228.00022 (20)</p><p>228 ≈ 4 3 ( 13 + 1 13 ) 2 = 228.00789 (21)</p><p>494 ≈ 2 9 ⋅ 13 ( 13 + 1 13 ) 2 = 494.01709 (22)</p><p>Based on the preliminary work by Gordon [<xref ref-type="bibr" rid="scirp.112815-ref42">42</xref>], Klein showed the connection between the regular icosahedron, one of the five Platonic bodies, and the solution of the quintic polynomial. Instead of following Klein’s quintic icosahedral solution, the substitution of the complex variable z 5 → x formally leads to a quartic polynomial</p><p>H ( x , 1 ) = x 4 − 228 x 3 + 494 x 2 + 228 x + 1 (23)</p><p>≈ x 4 − 4 3 ( 13 + 1 13 ) 2 x ( x 2 − 13 6 x − 1 ) + 1 (24)</p><p>The four root of this polynomial have been calculated giving</p><p>x 3 = − 1 x 2 ,     x 4 = − 1 x 1 (25)</p><p>x 3 = 2.58365 ≈ 228 − 4 3 13 2 = 2.66666 (26)</p><p>x 4 = 225.80782 ≈ 4 3 13 2 = 225.33333 (27)</p><p>In addition, it yields</p><p>∑ i = 1 4 x i = 228 (28)</p><p>The reader is frequently confronted with the Fibonacci number 13, which obviously plays an important role besides φ and φ 5 when assessing bio-coding and related storage and processing of information.</p><p>Turning to another polynomial equation corresponding to the vertices of an icosahedron [<xref ref-type="bibr" rid="scirp.112815-ref41">41</xref>]</p><p>w ( x ) = x ( x 10 + 11 x 5 − 1 ) (29)</p><p>Now again substituting z for x<sup>5</sup> in the term in brackets and solving the resulting quadratic equation (only bracket term)</p><p>z 2 + 11 z − 1 = 0 , (30)</p><p>where</p><p>11 = φ − 5 − φ 5 (31)</p><p>one can confirm the two roots as z 1 = φ 5 respectively z 2 = − φ − 5 (see also [<xref ref-type="bibr" rid="scirp.112815-ref4">4</xref>] ).</p><p>In a recent contribution Planatet al. [<xref ref-type="bibr" rid="scirp.112815-ref23">23</xref>] defined a model for the structure of a nucleosome as secondary unit consisting of 8 histone proteins with a DNA double helix wound around. The assigned group was G 8 = ( 8 ⋅ 48 ; 5589 ) ≅ Z 8 ⋊ 2 Ο , where the finite group Z<sub>8</sub> is of order 8, the binary octahedral group 2O is of order 48, and d = 37 is the dimension of the corresponding Pauli group. One can approximate the rank of the Gram matrix d 2 = 1369 and the entries of 1367 in the structure table 5 [<xref ref-type="bibr" rid="scirp.112815-ref23">23</xref>] ) by</p><p>8 ⋅ ( 13 + 1 13 ) 2 = 1368.047 ≈ 1368 (32)</p><p>8 ⋅ ( 13 + φ 4 3 + φ ) 2 = 1368.0013 (33)</p><p>Again one has a result showing the before derived square term based on number 13 (see Equation (21)). Furthermore, relating the coefficients of Equation (19) showing number 1368 one confirms simply 228 ⋅ 6 = 1368 respectively 494 ⋅ 6 2 13 = 1368 .</p></sec><sec id="s7"><title>7. Self-Duality as a Suggested Property for Image Storage, Memory and Consciousness</title><p>Self-duality is a very important concept of mathematics as well as physics and should be applied to biophysics respectively biochemistry in order to understand the very stable information storage within the human brain. Self-dual objects include polyhedra, graphs, configurations and codes. The skeleton of a self-dual polyhedron is a self-dual graph. For instance, self-dual solitons as self-reinforcing and shape-maintaining wave packets are expected to be very stable. Among the self-dual polyhedra are the regular tetrahedron respectively pyramids in general. Also the Kummer quartic surface with 16 nodes and 16 singular tangent conics, believed by Planatet al. [<xref ref-type="bibr" rid="scirp.112815-ref22">22</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref23">23</xref>] to explain in part the genetic code of secondary protein structures besides DNA, is self-dual [<xref ref-type="bibr" rid="scirp.112815-ref43">43</xref>].</p><p>The information storage respectively processing certainly doesn’t work via simple bits or qubits but via complex pictures generated by superposition of stable (soliton-like) wave packets, burned into a multiplex microtubule array or a comparable matrix. This happens against the background of the omnipresent dark energy with all the information collected up to then. Each speedy moving body or particle is surrounded by dark matter respectively energy [<xref ref-type="bibr" rid="scirp.112815-ref17">17</xref>], and when seeking for an assumed resonance field that links DNA or tubulin resonances with the work of the brain according to [<xref ref-type="bibr" rid="scirp.112815-ref6">6</xref>], the first candidate to fulfill all conditions is simply dark energy.</p></sec><sec id="s8"><title>8. What Is the Code for an Assumed Electron Helix?</title><p>Importantly, also elementary particles such as the electron are thought to exhibit a helical structure [<xref ref-type="bibr" rid="scirp.112815-ref44">44</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref45">45</xref>] indicating that nature used this principle of curling again and again [<xref ref-type="bibr" rid="scirp.112815-ref46">46</xref>]. Remarkably, the arithmetic mean between the proposed</p><p>maximal superluminal electron velocity and the minimal one yields v &#175; = c φ . The</p><p>application of IRT transformations [<xref ref-type="bibr" rid="scirp.112815-ref17">17</xref>] to the problem would certainly present the electron helix approach correctly and in full glory. We will work on this. The frequency of electron’s Zitterbewegung is found to equal that of the composing photons [<xref ref-type="bibr" rid="scirp.112815-ref44">44</xref>]. Besides the results given in [<xref ref-type="bibr" rid="scirp.112815-ref47">47</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref48">48</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref49">49</xref>] and contrasting the QED coding that uses an unbelievable cascade of Feynman diagrams [<xref ref-type="bibr" rid="scirp.112815-ref50">50</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref51">51</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref52">52</xref>] one should try to encode and understand a numerical golden mean relation for the electron as a quite stable helically wound and less spherically than icosahedron-shaped compacted entity where Δ g e is the gyromagnetic correction factor of the electron. Using just derived algebraic-geometrical relations, one can our fully golden mean based approximation of Δ g e [<xref ref-type="bibr" rid="scirp.112815-ref47">47</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref48">48</xref>] equip with a more structured meaning pointing to a possible virus-like structure of the electron</p><p>Δ g e ≈ φ 6 24 ≈ 5 3 ⋅ 3 + φ 8 ( 13 + 1 13 ) 2 = 0.0023174 (34a)</p><p>respectively</p><p>Δ g e ≈ φ − exp ( − φ ) 34 + φ 5 = 0.00231829 (34b)</p><p>The experimental value of Δ g e was determined slightly larger [<xref ref-type="bibr" rid="scirp.112815-ref51">51</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref52">52</xref>], but a new relativistic correction was proposed shifting this value towards the considered smaller one [<xref ref-type="bibr" rid="scirp.112815-ref48">48</xref>].</p><p>If we proceed with this helix quantum-vortex approach we may at least understand electron’s pairing in superconductors, too [<xref ref-type="bibr" rid="scirp.112815-ref53">53</xref>]. Historically, already in 1978 L. S. Levitt had raised the question whether the photon is a double helix [<xref ref-type="bibr" rid="scirp.112815-ref54">54</xref>]. A photon with high energy decomposes by interaction with matter to an electron and a positron, both helically twisted. Recently, Williamson suggested a possible structure of the spherical electron (positron) by an elaborated new linear theory of light and matter [<xref ref-type="bibr" rid="scirp.112815-ref55">55</xref>], but used once again the questionable relativistic</p><p>factor γ = 1 2 ( R + 1 R ) , where the Doppler factor is given as = 1 + β 1 − β , and β = v c .</p><p>However, if one could ultimately prove the double helix structure of the electron, it would seem natural to think further of its possible fine structure making one electron not equal to another one when interacting with the environment, despite their same mass and bulk properties. It would revolutionize our ideas when it comes to storing and processing exorbitantly large amounts of information.</p></sec><sec id="s9"><title>9. Helical Helix Construct</title><p>Single respectively double-strand helices may not only be found in nature as rotational blurred linearly aligned fibers. The fiber axis of a helix or double-helix may itself be proposed in turn helically wound to strengthen its spring-like elastic behavior suggested for application in building constructions. Such construct would not represent the densest packing, but an extremely flexible one. I am not sure whether nature used this construct, for instance as DNA partial packing in viruses or in the structure of the electron, but designers could certainly gain profit in its application. Also energy harvesting may be possible when such construct was set in vibration by wind or water.</p></sec><sec id="s10"><title>10. Conclusion</title><p>The given suggestions are intended to provide an expanded view on the already complicated matter of coding important helical structures of life and matter exemplified by the DNA or the beautiful electron. The duality of matter and surrounding waves or matter and dark matter leaves fingerprints in such structures in form of numerical reciprocity given by the golden mean φ − 1 = φ + 1 = ∅ , besides φ − 5 + φ 5 = 11 (phase transitions from microscopic to cosmic scale, dimension</p><p>of superstring theory) or 2 3 ( 13 + 1 13 ) 2 ≈ 228 (coefficient of the icosahedron</p><p>equation). Number 13 is also found as proto-filament number in helically twisted tubulin microtubules as the locus where human information storage and assessment is suspected. Philosophically one could say that life beats 13. The reciprocity symmetry principles may find application in topological quantum computers based on Fibonacci anyons simulating processes that determine the speed and storage capacity of human mind.</p></sec><sec id="s11"><title>Acknowledgements</title><p>Many colleagues inspired this contribution, focussing all the years on the importance and beauty of the golden mean or golden ratio present in all areas of life, physics and the entire cosmos. Especially the author gratefully acknowledges the stimulating work of El Naschie, Scott Olsen, Leila Marek-Crnjac, Ji-HuanHe, and Michael Sherbon.</p></sec><sec id="s12"><title>Conflicts of Interest</title><p>The author declares no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s13"><title>Cite this paper</title><p>Otto, H.H. (2021) Beyond a Quartic Polynomial Modeling of the DNA Double-Helix Genetic Code. Journal of Applied Mathematics and Physics, 9, 2558-2577. https://doi.org/10.4236/jamp.2021.910165</p></sec><sec id="s14"><title>Appendix</title><p>Golden Mean Beauty and Its Intrinsic Reciprocity Property [<xref ref-type="bibr" rid="scirp.112815-ref48">48</xref>]</p><p>The golden mean or golden ratio φ is an omnipresent number in nature, found in the architecture of living creatures as well as human buildings, music, finance, medicine, philosophy, and of course in physics and mathematics [<xref ref-type="bibr" rid="scirp.112815-ref56">56</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref57">57</xref>]. It is the most irrational number known and a number-theoretical chameleon with a self-similarity property. On the other hand, its infinite continued fraction representation is the simplest of all and is represented together with that for its fifth power by [<xref ref-type="bibr" rid="scirp.112815-ref58">58</xref>]</p><p>φ = 5 − 1 2 = 1 1 + 1 1 + 1 1 + ⋯ ,       φ 5 = 1 11 + 1 11 + 1 11 + ⋯ (35)</p><p>It impressively underlines the fractal character of both universal numbers. Most obviously, the golden mean mediates stability of a system, because only “particles” as the center of gravity of vibrations with the most irrational winding survive. Important numerical relations involving φ are summarized below. However, to prevent confusion, in textbooks of mathematics the reciprocal value for φ is frequently used.</p><p>φ = 5 − 1 2 = 0.618033988 ⋯ ,       φ − 1 = 1 + φ = 5 + 1 2 = 1.618033988 ⋯ (36)</p><p>φ 2 = 1 − φ = 0.381966011 ⋯ ,       φ − 2 = 2 + φ = 2.618033988 ⋯ (37)</p><p>( φ 2 + 1 ) − 1 = ( φ − 2 + 1 ) / 2 (38)</p><p>or equivalently</p><p>( φ − 2 + 1 ) − 1 = ( φ 2 + 1 ) / 5 (39)</p><p>φ 5 = 1 − φ 1 + φ φ 2 = 0.090169943 ⋯ [<xref ref-type="bibr" rid="scirp.112815-ref2">2</xref>] (40)</p><p>φ 5 2 + 5 2 φ 2 = 1 [<xref ref-type="bibr" rid="scirp.112815-ref59">59</xref>] (41)</p><p>φ 3 + 2 φ 2 = 1 (42)</p><p>Connecting the fifth power of φ with the circle constant π on can confirm</p><p>π ⋅ φ 5 = 0.283277 ≈ 2 π − 6 = 0.283185 (43)</p><p>and further</p><p>φ 3 ≈ 5 3 ( π − 3 ) (44)</p><p>The product of these fundamental numbers is found as volume quotient of the in-sphere of the Great Pyramid to the pyramid volume itself [<xref ref-type="bibr" rid="scirp.112815-ref5">5</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref21">21</xref>].</p><p>Solution of a Special Quadric Polynomial Equation</p><p>The approach 4 3 ( x + x − 1 ) 2 = 228 of Equation (21) can be recast into the quadric polynomial equation</p><p>x 4 − 169 x 2 + 1 = 0 (45)</p><p>with solutions x 1 , 2 = &#177; 12.99977241 ≈ &#177; 13 and x 3 , 4 = x 1 , 2 − 1 = &#177; 0.076924423 . Using this result one can exactly generate also the coefficients 494 respectively 1368 as</p><p>2 9 ⋅ 13 ⋅ ( x + x 1 − 1 ) 2 = 494 (46)</p><p>8 ⋅ ( x + x 1 − 1 ) 2 = 1368 (47)</p><p>In contrast, when applying instead the quadratic equation x 2 + 13 x − 1 = 0 similar to Equation (30), then this equation has solutions of x 1 = − 1 0.076473218 = − 13.076473218 and x 2 = 0.076473218... , which can also be tackled by an infinite continued fraction representation [<xref ref-type="bibr" rid="scirp.112815-ref58">58</xref>].</p><p>About Double Well Potentials</p><p>Because the polynomial f(x) (Equation (1)) looks like an asymmetric double well potential curve, let us linger a little bit on such linear superposition of “classical” states as a concept important in quantum information theory [<xref ref-type="bibr" rid="scirp.112815-ref60">60</xref>].</p><p>On can suggest from the expression for the baryonic matter energy density [<xref ref-type="bibr" rid="scirp.112815-ref17">17</xref>] a quartic polynomial of a symmetric double-well form (FigureA1) with a maximum at x = φ</p><p>p ( x ) = ( x − 1 ) ( x − φ 3 ) ( x − φ − 1 + 1 13 ) ( x + φ 2 − 1 13 ) (48)</p><p>p ( x ) = x 4 − 2.47213596 x 3 + 1.29382703 x 2 + 0.289285566 x − 0.11097179 (49)</p><p>where the coefficient of the x 3 term is 2 ( 1 + φ 3 ) and the last term can be approximated by 1 13 ⋅ ln ( 2 ) = 0.1109765 ⋯</p><p>FigureA1 depicts the quartic polynomial p(x) besides an altered polynomial with a slightly increased coefficient of the quadratic term to get an asymmetrical double-well curve similar to f(x). Both curves can be compared with the Hardy function [<xref ref-type="bibr" rid="scirp.112815-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.112815-ref17">17</xref>] indicating also a maximum at x = φ and a high of y max = φ 5</p><p>h ( x ) = ( 1 − x ) x 2 / ( 1 + x ) (50)</p><p>One can alter the p(x) polynomial to adapt well the physically relevant part of Hardy’s function for x ≤ 1 . For instance, the following simple quartic double well polynomial maps the Hardy function well in the range | x | ≤ 0.2 (see FigureA2) indicating its maximum at x = 1 / 2 instead of x = φ for the Hardy function</p><p>q ( x ) = x 4 − 2 x 3 + x 2 (51)</p><p>When replacing the symmetric double well by an asymmetric curve according to</p><p>q + ( x ) = x 4 − 2 x 3 + ( 1 + φ 5 ) x 2 (52)</p><p>then Hardy’s functions can be well approximated still beyond the maximum exactly located at x = φ with a high of φ 5 .</p><p>Another approximation was depicted in FigureA2 in blue concerning the Hardy function</p><p>h ˜ ( x ) = ( 1 − x ) x 2 exp ( − x ) (53)</p><p>Instead of replacing ( 1 + x ) − 1 by exp ( − x ) [<xref ref-type="bibr" rid="scirp.112815-ref61">61</xref>] we have applied its series expansion, leading to the following excellent polynomial approximation</p><p>h ˜ ( x ) ≈ ∑ n = 1 ∞ x 2 ⋅ ( 1 − x 2 ) n = x 2 ( ( 1 − x ) 2 + ( 1 − x ) 2 4 + ( 1 − x ) 3 8 + ( 1 − x ) 4 16 + ( 1 − x ) 5 32 &#177; ⋯ ) (54)</p><p>which is depicted in FigureA3 in comparison with Hardy’s function.</p></sec></body><back><ref-list><title>References</title><ref id="scirp.112815-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Planat, M., Aschheim, R.A., Amaral, M.M., Fang, F. and Irwin, K. 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